Xiangming Ji

Associate Professor of Nutritional Sciences

Xiangming Ji

Research Summary

Metabolic reprogramming in the airway epithelial compartment, which is central to the development of lung diseases such as cystic fibrosis (CF), chronic obstructive pulmonary disease (COPD), and lung cancer

Huck Affiliations

Links

Most Recent Publications

Metabolic signatures of acute respiratory distress syndrome: COVID versus non-COVID

Xiangming Ji, Hong Long Ji, 2024, American Journal of Physiology on p. L596-L603

Inhalation of nicotine-containing electronic cigarette vapor exacerbates the features of COPD by inducing ferroptosis in βENaC-overexpressing mice

Hongwei Han, Maureen Meister, Guangda Peng, Yi Yuan, Jingjuan Qiao, Jenny J. Yang, Zhi Ren Liu, Xiangming Ji, 2024, Frontiers in Immunology

Early Detection and Staging of Lung Fibrosis Enabled by Collagen-Targeted MRI Protein Contrast Agent

Oluwatosin Y. Ibhagui, Dongjun Li, Hongwei Han, Guangda Peng, Maureen L. Meister, Zongxiang Gui, Jingjuan Qiao, Mani Salarian, Bin Dong, Yi Yuan, Yiting Xu, Hua Yang, Shanshan Tan, Ganesh Satyanarayana, Shenghui Xue, Ravi Chakra Turaga, Malvika Sharma, Yan Hai, Yuguang Meng, Khan Hekmatyar, Phillip Sun, Gabriel Sica, Xiangming Ji, Zhi Ren Liu, Jenny J. Yang, 2023, Chemical and Biomedical Imaging on p. 268-285

Correction to: Characterization of metabolites and biomarkers for the probiotic effects of Clostridium cochlearium on high-fat diet-induced obese C57BL/6 mice (European Journal of Nutrition, (2022), 61, 4, (2217-2229), 10.1007/s00394-022-02840-z)

Fei Yang, Wenjun Zhu, Paba Edirisuriya, Qing Ai, Kai Nie, Xiangming Ji, Kequan Zhou, 2022, Zeitschrift fur Ernahrungswissenschaft on p. 2231

Characterization of metabolites and biomarkers for the probiotic effects of Clostridium cochlearium on high-fat diet-induced obese C57BL/6 mice

Fei Yang, Wenjun Zhu, Paba Edirisuriya, Qing Ai, Kai Nie, Xiangming Ji, Kequan Zhou, 2022, Zeitschrift fur Ernahrungswissenschaft on p. 2217-2229

Beneficial effects of a combination of Clostridium cochlearium and Lactobacillus acidophilus on body weight gain, insulin sensitivity, and gut microbiota in high-fat diet–induced obese mice

Fei Yang, Wen Jun Zhu, Paba Edirisuriya, Qing Ai, Kai Nie, Xiang Ming Ji, Yong Li, Kequan Zhou, 2022, Nutrition

Sars-cov2 infection alters tryptophan catabolism and phospholipid metabolism

Gagandeep Kaur, Xiangming Ji, Irfan Rahman, 2021, Metabolites

Electronic Cigarette Exposure Enhances Lung Inflammatory and Fibrotic Responses in COPD Mice

Hongwei Han, Guangda Peng, Maureen Meister, Hongwei Yao, Jenny J. Yang, Ming Hui Zou, Zhi Ren Liu, Xiangming Ji, 2021, Frontiers in Pharmacology

Tocotrienols: Dietary supplements for chronic obstructive pulmonary disease

Xiangming Ji, Hongwei Yao, Maureen Meister, Douglas S. Gardenhire, Huanbiao Mo, 2021, Antioxidants

Dysregulated metabolites serve as novel biomarkers for metabolic diseases caused by e-cigarette vaping and cigarette smoking

Qixin Wang, Xiangming Ji, Irfan Rahman, 2021, Metabolites

Most-Cited Papers

xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression

Xiangming Ji, Jun Qian, S. M.Jamshedur Rahman, Peter J. Siska, Yong Zou, Bradford K. Harris, Megan D. Hoeksema, Irina A. Trenary, Chen Heidi, Rosana Eisenberg, Jeffrey C. Rathmell, Jamey D. Young, Pierre P. Massion, 2018, Oncogene on p. 5007-5019

Targeting SLC1a5-mediated glutamine dependence in non-small cell lung cancer

Mohamed Hassanein, Jun Qian, Megan D. Hoeksema, Jing Wang, Marie Jacobovitz, Xiangming Ji, Fredrick T. Harris, Bradford K. Harris, Kelli L. Boyd, Heidi Chen, Rosana Eisenberg, Pierre P. Massion, 2015, International Journal of Cancer on p. 1587-1597

Methionine restriction and cancer biology

Desiree Wanders, Katherine Hobson, Xiangming Ji, 2020, Nutrients

The RNA binding protein FXR1 is a new driver in the 3q26-29 amplicon and predicts poor prognosis in human cancers

Jun Qian, Mohamed Hassanein, Megan D. Hoeksema, Bradford K. Harris, Yong Zou, Heidi Chen, Pengcheng Lu, Rosana Eisenberg, Jing Wang, Allan Espinosa, Xiangming Ji, Fredrick T. Harris, S. M. Jamshedur Rahman, Pierre P. Massiona, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. 3469-3474

Fluorescence-based measurement of cystine uptake through xCT shows requirement for ROS detoxification in activated lymphocytes

Peter J. Siska, Bumki Kim, Xiangming Ji, Megan D. Hoeksema, Pierre P. Massion, Kathryn E. Beckermann, Jianli Wu, Jen Tsan Chi, Jiyong Hong, Jeffrey C. Rathmell, 2016, Journal of Immunological Methods on p. 51-58

The airway epithelium undergoes metabolic reprogramming in individuals at high risk for lung cancer

S. M.Jamshedur Rahman, Xiangming Ji, Lisa J. Zimmerman, Ming Li, Bradford K. Harris, Megan D. Hoeksema, Irina A. Trenary, Yong Zou, Jun Qian, Robbert J.C. Slebos, Jennifer Beane, Avrum Spira, Yu Shyr, Rosana Eisenberg, Daniel C. Liebler, Jamey D. Young, Pierre P. Massion, 2016, JCI insight

Oil palm phenolics (OPP) inhibit pancreatic cancer cell proliferation via suppression of NF-κB pathway

Xiangming Ji, Anee Usman, Nurul H. Razalli, Ravigadevi Sambanthamurthi, Smiti V. Gupta, 2015, Anticancer Research on p. 97-106

A 3q gene signature associated with triple negative breast cancer organ specific metastasis and response to neoadjuvant chemotherapy

Jun Qian, Heidi Chen, Xiangming Ji, Rosana Eisenberg, A. Bapsi Chakravarthy, Ingrid A. Mayer, Pierre P. Massion, 2017, Scientific Reports

Identification of lipid biomarker from serum in patients with chronic obstructive pulmonary disease

Ding Liu, Maureen Meister, Shiying Zhang, Chi In Vong, Shuaishuai Wang, Ruixie Fang, Lei Li, Peng George Wang, Pierre Massion, Xiangming Ji, 2020, Respiratory Research

Electronic Cigarette Exposure Enhances Lung Inflammatory and Fibrotic Responses in COPD Mice

Hongwei Han, Guangda Peng, Maureen Meister, Hongwei Yao, Jenny J. Yang, Ming Hui Zou, Zhi Ren Liu, Xiangming Ji, 2021, Frontiers in Pharmacology