Ruth Nissly
Assistant Research Professor
- She/Her
- rah38@psu.edu
Huck Affiliations
Most Recent Publications
Distinct Replication Kinetics, Cytopathogenicity, and Immune Gene Regulation in Human Microglia Cells Infected with Asian and African Lineages of Zika Virus
Ian M. Bird, Victoria Cavener, Meera Surendran Nair, Ruth H. Nissly, Shubhada K. Chothe, Joshy Jacob, Suresh Varma Kuchipudi, 2024, Microorganisms
The Susceptibility of Chickens to Zika Virus: A Comprehensive Study on Age-Dependent Infection Dynamics and Host Responses
Ruth H. Nissly, Levina Lim, Margo R. Keller, Ian M. Bird, Gitanjali Bhushan, Sougat Misra, Shubhada K. Chothe, Miranda C. Sill, Nagaram Vinod Kumar, A. V.N. Sivakumar, B. Rambabu Naik, Bhushan M. Jayarao, Suresh V. Kuchipudi, 2024, Viruses
Impact of an autophagy-inducing peptide on immunogenicity and protection efficacy of an adenovirus-vectored SARS-CoV-2 vaccine
Ekramy E. Sayedahmed, Marcelo Valdemir Araújo, Taiana Tainá Silva-Pereira, Shubhada K. Chothe, Ahmed Elkashif, Marwa Alhashimi, Wen Chien Wang, Andrea P. Santos, Meera Surendran Nair, Abhinay Gontu, Ruth Nissly, Antônio Francisco de Souza Filho, Mariana Silva Tavares, Marina Caçador Ayupe, Caio Loureiro Salgado, Érika Donizetti de Oliveira Candido, Danielle Bruna Leal Oliveira, Edison Luiz Durigon, Marcos Bryan Heinemann, Denise Morais da Fonseca, Chinnaswamy Jagannath, Ana Marcia Sá Guimarães, Suresh V. Kuchipudi, Suresh K. Mittal, 2023, Molecular Therapy Methods and Clinical Development on p. 194-207
Comparative transcriptome analysis of spleen of Newcastle Disease Virus (NDV) infected chicken and Japanese quail: a potential role of NF-κβ pathway activation in NDV resistance
Manesh Kumar Panner Selvam, Vijayrani Kanagaraj, Kumanan Kathaperumal, Ruth H. Nissly, Janet M. Daly, Suresh V. Kuchipudi, 2023, VirusDisease on p. 402-409
Inactivation of HCoV-NL63 and SARS-CoV-2 in aqueous solution by 254 nm UV-C
Lily X. Li, Ruth H. Nissly, Anand Swaminathan, Ian M. Bird, Nina R. Boyle, Meera Surendran Nair, Denver I. Greenawalt, Abhinay Gontu, Victoria S. Cavener, Ty Sornberger, James D. Freihaut, Suresh V. Kuchipudi, William P. Bahnfleth, 2023, Journal of Photochemistry and Photobiology B: Biology
SARS-CoV-2 Prevalence and Variant Surveillance among Cats in Pittsburgh, Pennsylvania, USA
Santhamani Ramasamy, Abhinay Gontu, Sabarinath Neerukonda, Diana Ruggiero, Becky Morrow, Sheweta Gupta, Saranya Amirthalingam, John M. Hardham, Joshua T. Lizer, Michele Yon, Ruth H. Nissly, Padmaja Jakka, Shubhada K. Chothe, Lindsey C. LaBella, Deepanker Tewari, Meera Surendran Nair, Suresh Varma Kuchipudi, 2023, Viruses
Complete Genome Sequence of a Bovine Coronavirus Isolated from a Goat in Pennsylvania, USA
Shubhada Chothe, Maurice Byukusenge, Manoj Sekhwal, L Li, Lindsey LaBella, Padmaja Jakka, Kay Palchak, Rhiannon Barry, Michele Yon, Ruth H. Nissly, Kathleen Kelly, Bhushan M. Jayarao, Meera Nair, Suresh Varma Kuchipudi, 2023, Genome Announcements
Little Brown Bats (Myotis lucifugus) Support the Binding of SARS-CoV-2 Spike and Are Likely Susceptible to SARS-CoV-2 Infection
Shubhada K. Chothe, Padmaja Jakka, Veda Sheersh Boorla, Santhamani Ramasamy, Abhinay Gontu, Ruth H. Nissly, Justin Brown, Gregory Turner, Brent J. Sewall, Dee Ann M. Reeder, Kenneth A. Field, Julie B. Engiles, Saranya Amirthalingam, Abirami Ravichandran, Lindsey LaBella, Meera Surendran Nair, Costas D. Maranas, Suresh V. Kuchipudi, 2023, Viruses
Optimized conditions for Listeria, Salmonella and Escherichia whole genome sequencing using the Illumina iSeq100 platform with point-and-click bioinformatic analysis
Sonsiray Alvarez Narvaez, Zhenyu Shen, Lifang Yan, Brianna L.S. Stenger, Laura B. Goodman, Ailam Lim, Ruth H. Nissly, Meera Surendran Nair, Shuping Zhang, Susan Sanchez, 2022, PLoS One
Mitigating the Impact of Emerging Animal Infectious Disease Threats: First Emerging Animal Infectious Diseases Conference (EAIDC) Report
Suresh V. Kuchipudi, Deanna Behring, Ruth Nissly, Shubhada K. Chothe, Abhinay Gontu, Abirami Ravichandran, Ty Butler, 2022, Viruses
Most-Cited Papers
Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer
Suresh V. Kuchipudi, Meera Surendran-Nair, R Ruden, M Yon, R Nissly, Kurt J. Vandegrift, R Nelli, Lingling Li, Bhushan Jayarao, Costas D. Maranas, N Levine, K Willgert, Andrew J.K. Conlan, Conlan AJK, R Olsen, J Davis, J Musser, Peter John Hudson, Vivek Kapur, 2022, Proceedings of the National Academy of Sciences of the United States of America
Convalescent plasma anti–SARS-CoV-2 spike protein ectodomain and receptor-binding domain IgG correlate with virus neutralization
Eric Salazar, 23 names , Suresh Kuchipudi, Isabella Cattadori, Paul Christensen, Todd Eagar, Xin Yi, Picheng Zhao, Zhicheng Jin, S. Long, Randall Olsen, Jian Chen, Brian Castillo, Christopher Leveque, Dalton Towers, Jason Lavinder, Jimmy Gollihar, Jose Cardona, Gregory Ippolito, Ruth Nissly, Ian Bird, Denver Greenawalt, Randall Rossi, Abhinay Gontu, Sreenidhi Srinivasan, Indira Poojary, I Cattadori, Peter J. Hudson, Nicole Josleyn, Laura Prugar, Kathleen Huie, Andrew Herbert, David Bernard, John Dye, Vivek Kapur, James Musser, 2020, Journal of Clinical Investigation on p. 6728-6738
Acoustofluidic Fluorescence Activated Cell Sorter
Ahmad Ahsan Nawaz, Yuchao Chen, Nitesh Nama, Ruth Helmus Nissly, Liqiang Ren, Adem Ozcelik, Lin Wang, J. Philip McCoy, Stewart J. Levine, Tony Jun Huang, 2015, Analytical Chemistry on p. 12051-12058
SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination
Wei Chiao Huang, Shiqi Zhou, Xuedan He, Kevin Chiem, Moustafa T. Mabrouk, Ruth H. Nissly, Ian M. Bird, Mike Strauss, Suryaprakash Sambhara, Joaquin Ortega, Elizabeth A. Wohlfert, Luis Martinez-Sobrido, Suresh V. Kuchipudi, Bruce A. Davidson, Jonathan F. Lovell, 2020, Advanced Materials on p. e2005637
Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells
Sujit Pujhari, Marco Brustolin, Vanessa M. Macias, Ruth H. Nissly, Masashi Nomura, Suresh V. Kuchipudi, Jason Rasgon, 2019, Emerging Microbes and Infections on p. 8-16
Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike RBD and human ACE2
Chen Chen, Veda Sheersh Boorla, Deepro Banerjee, Ratul Chowdhury, Victoria S. Cavener, Ruth H. Nissly, Abhinay Gontu, Nina R. Boyle, Kurt Vandegrift, Meera Surendran Nair, Suresh V. Kuchipudi, Costas D. Maranas, 2021, Proceedings of the National Academy of Sciences of the United States of America
Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice
Moustafa T. Mabrouk, Kevin Chiem, Edurne Rujas, Wei Chiao Huang, Dushyant Jahagirdar, Breandan Quinn, Meera Surendran Nair, Ruth H. Nissly, Victoria S. Cavener, Nina R. Boyle, Ty A. Sornberger, Suresh V. Kuchipudi, Joaquin Ortega, Jean Philippe Julien, Luis Martinez-Sobrido, Jonathan Lovell, 2021, Science advances
Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy
Abhinay Gontu, Sreenidhi Srinivasan, Eric Salazar, Meera Surendran Nair, Ruth Nissly, Denver Greenawalt, Ian Bird, Catherine Herzog, Matthew J. Ferrari, Indira Poojary, others, Robab Katani, Scott E. Lindner, Allen M. Minns, Randall Rossi, Paul A. Christensen, Brian Castillo, Jian Chen, Todd N. Eagar, Xin Yi, Picheng Zhao, Christopher Leveque, Randall J. Olsen, David W. Bernard, Jimmy Gollihar, Suresh V. Kuchipudi, James M. Musser, Vivek Kapur, 2021, Communications Biology on p. 1--9
Influenza C and D viral load in cattle correlates with bovine respiratory disease (BRD): Emerging role of orthomyxoviruses in the pathogenesis of BRD
Ruth Nissly, Noriza Zaman, Ibrahim, Puteri Ainaa S., Puteri Ainaa S. Ibrahim, Ibrahim PAS, Kaitlin McDaniel, Levina Lim, Jennifer Kiser, Ian Bird, Shubhada Chothe, Gitanjali Bhushan, Kurt Vandegrift, Holly Neibergs, Kuchipudi, Suresh, V, Suresh V. Kuchipudi, 2020, Virology on p. 10-15
SARS-CoV-2 Omicron (B.1.1.529) Infection of Wild White-Tailed Deer in New York City
Kurt Vandegrift, Michele Yon, Surendran Nair, Meera, M Surendran Nair, Abhinay Gontu, Santhamani Ramasamy, Saranya Amirthalingam, Sabarinath Neerukonda, Ruth Nissly, Shubhada Chothe, Padmaja Jakka, Lindsey LaBella, Nicole Levine, Sophie Rodriguez, C Chen, Sheersh Boorla, Veda, V Sheersh Boorla, Tod Stuber, Jason Boulanger, Nathan Kotschwar, Sarah Aucoin, Richard Simon, Katrina Toal, Randall Olsen, J Davis, Dashzeveg Bold, Natasha Gaudreault, Dinali Perera, Krishani, K Dinali Perera, Yunjeong Kim, Kyeong-Ok Chang, Costas Maranas, Juergen Richt, James Musser, P Hudson, Vivek Kapur, Suresh V. Kuchipudi, 2022, Viruses on p. 13
News Articles Featuring Ruth Nissly
Jul 19, 2024
Q&A: Will H5N1 avian influenza evolve to become more dangerous to humans?
Penn State News spoke with Ruth Nissly, assistant research professor of veterinary and biomedical sciences, to learn more about how scientists are monitoring the H5N1 virus.
Full Article
Aug 22, 2023
One Health Microbiome Center's 2023-24 Interdisciplinary Innovation Fellows
The One Health Microbiome Center (OHMC) in the Huck Institutes of the Life Sciences at Penn State has named five recipients for its 2023-24 Interdisciplinary Innovation Fellowships (IIF) program.
Full Article
Apr 07, 2022
Preventing, controlling spread of animal diseases focus of forum at Penn State
Exploring the emergence, spread and control of animal infectious diseases was the focus of the inaugural Emerging Animal Infectious Disease Conference held Nov. 29-Dec.1, 2021, at Penn State. It was hosted by the College of Agricultural Sciences, the Pennsylvania Department of Agriculture, and Penn State’s Center for Security Research and Education.
Full Article
Nov 03, 2021
Deer may be reservoir for SARS-CoV-2, study finds
The findings of a study by Penn State and Iowa researchers suggest that white-tailed deer may be a reservoir for the SARS-CoV-2 virus to continually circulate, and raises concerns of emergence of new strains that may prove a threat to wildlife and, possibly, to humans.
Full Article