Patrick Randall
Assistant Professor of Anesthesiology
![Patrick Randall](https://www.huck.psu.edu/assets/uploads/staff/_480x480_crop_center-center_100_none/par5356.png)
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C2817A - 500 University Drive
Hershey, PA 17078 - He/Him/His
- prandall@psu.edu
- 717-531-0003 ext 289119
Research Summary
The role of neuroimmune signaling in alcohol and nicotine use with a focus on co-use
Huck Affiliations
Links
Publication Tags
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Alcohols Self Administration Nicotine Brain Alcohol Therapeutics Bupropion Gene Expression Ethanol Toll Like Receptor 3 Decision Making Pharmaceutical Preparations Corpus Striatum Agonist Genes Poly I C Rats Tetrabenazine Nucleus Accumbens Long Evans Rats Cerebral Cortex Depression Dopamine Neurons AlcoholismMost Recent Publications
Differential effects of nicotine, alcohol, and co-exposure on neuroimmune-related protein and gene expression in corticolimbic brain regions in rats
Christie Randall, Dongxiao Sun, Patrick Randall, ACS Chemical Neuroscience
Alcohol, Nicotine, and COVID-19: A retrospective study of health outcomes in central Pennsylvania
Kevin Xu, Patrick Randall, Brain Research Bulletin
Adolescent alcohol disrupts development of noradrenergic neurons in the nucleus of the tractus solitarius and enhances stress behaviors in adulthood in mice in a sex specific manner
Liz A. Aguilar, Elizabeth Aguilar, Caitlin R. Coker, Yuval Silberman, Zari McCullers, Alexandra Evans, Opeyemi Showemimo, Mariam Melkumyan, Bailey N. Keller, Angela E. Snyder, Sarah S. Bingaman, Patrick A. Randall, Andras Hajnal, Kirsteen N. Browning, Amy C. Arnold, 2023, Addiction Neuroscience
Alcohol, nicotine, and COVID-19: A retrospective study of health outcomes in central Pennsylvania
Kevin Lou Xu, Patrick Arthur Randall, 2023, Journal of Electrophysiological Techniques on p. 175-183
Increased alcohol self-administration following repeated Toll-like receptor 3 agonist treatment in male and female rats
Dennis F. Lovelock, Patrick A. Randall, Kalynn Van Voorhies, Ryan P. Vetreno, Fulton T. Crews, Joyce Besheer, 2022, Pharmacology Biochemistry and Behavior
Ethanol inhibits pancreatic projecting neurons in the dorsal motor nucleus of the vagus
Bailey Keller, Patrick Randall, Kirsteen Browning, Amy Arnold, A Arnold, Kirsteen N. Browning, Yuval Silberman, 2022, Journal of Electrophysiological Techniques on p. 121-129
Differential Effects of Nicotine, Alcohol, and Coexposure on Neuroimmune-Related Protein and Gene Expression in Corticolimbic Brain Regions of Rats
Christie A. Randall, Dongxiao Sun, Patrick A. Randall, 2022, ACS Chemical Neuroscience
Low-dose alcohol: Interoceptive and molecular effects and the role of dentate gyrus in rats
Patrick Randall, D Lovelock, K VanVoorhies, V Agan, T Kash, J Besheer, 2021, Addiction Biology on p. e12965
Acute and chronic bupropion treatment does not prevent morphine-induced conditioned place preference in mice
Greer McKendrick, Sonakshi Sharma, Dongxiao Sun, Patrick A. Randall, Nicholas M. Graziane, 2020, European Journal of Pharmacology
Role of mPFC and nucleus accumbens circuitry in modulation of a nicotine plus alcohol compound drug state
Patrick Randall, Z McElligott, J Besheer, 2020, Addiction Biology on p. e12782
Most-Cited Papers
Effort-related motivational effects of the pro-inflammatory cytokine interleukin 1-beta: Studies with the concurrent fixed ratio 5/ chow feeding choice task
E Nunes, Patrick Randall, A Estrada, B Epling, E Hart, C Lee, Y Baqi, C Müller, M Correa, J Salamone, 2014, Psychopharmacology on p. 727-36
Bupropion increases selection of high effort activity in rats tested on a progressive ratio/chow feeding choice procedure: Implications for treatment of effort-related motivational symptoms
Patrick A. Randall, Christie A. Lee, Samantha J. Podurgiel, Evan Hart, Samantha E. Yohn, Myles Jones, Margaret Rowland, Laura Lopez-Cruz, Merce Correa, John D. Salamone, 2015, International Journal of Neuropsychopharmacology on p. 1-11
The VMAT-2 inhibitor tetrabenazine affects effort-related decision making in a progressive ratio/chow feeding choice task: Reversal with antidepressant drugs
Patrick Randall, C Lee, E Nunes, S Yohn, V Nowak, B Khan, P Shah, S Pandit, V Vemuri, A Makriyannis, Y Baqi, C Müller, M Correa, J Salamone, 2014, PLoS One on p. e99320
The VMAT-2 inhibitor tetrabenazine alters effort-related decision making as measured by the T-maze barrier choice task: Reversal with the adenosine A<sub>2A</sub> antagonist MSX-3 and the catecholamine uptake blocker bupropion
S Yohn, C Thompson, Patrick Randall, C Lee, C Müller, Y Baqi, M Correa, J Salamone, 2015, Psychopharmacology on p. 1313-23
Sex differences in alcohol self-administration and relapse-like behavior in Long-Evans rats
Patrick A. Randall, Robert T. Stewart, Joyce Besheer, 2017, Pharmacology Biochemistry and Behavior on p. 1-9
Functional role for cortical-striatal circuitry in modulating alcohol self-administration
Anel A. Jaramillo, Patrick A. Randall, Spencer Stewart, Brayden Fortino, Kalynn Van Voorhies, Joyce Besheer, 2018, Neuropharmacology on p. 42-53
Silencing the insular-striatal circuit decreases alcohol self-administration and increases sensitivity to alcohol
Anel A. Jaramillo, Kalynn Van Voorhies, Patrick A. Randall, Joyce Besheer, 2018, Behavioural Brain Research on p. 74-81
Modulation of sensitivity to alcohol by cortical and thalamic brain regions
Anel A. Jaramillo, Patrick A. Randall, Suzanne Frisbee, Joyce Besheer, 2016, European Journal of Neuroscience on p. 2569-2580
The Toll-Like Receptor 3 Agonist Poly(I:C) Induces Rapid and Lasting Changes in Gene Expression Related to Glutamatergic Function and Increases Ethanol Self-Administration in Rats
Patrick A. Randall, Ryan P. Vetreno, Viren H. Makhijani, Fulton T. Crews, Joyce Besheer, 2019, Alcoholism: Clinical and Experimental Research on p. 48-60
The role of varenicline on alcohol-primed self-administration and seeking behavior in rats
Patrick A. Randall, Anel A. Jaramillo, Suzanne Frisbee, Joyce Besheer, 2015, Psychopharmacology on p. 2443-2454