Patrick Randall

Assistant Professor of Anesthesiology

Patrick Randall

Research Summary

The role of neuroimmune signaling in alcohol and nicotine use with a focus on co-use

Huck Affiliations

Links

Most Recent Publications

Alcohol, Nicotine, and COVID-19: A retrospective study of health outcomes in central Pennsylvania

Kevin Xu, Patrick Randall, Brain Research Bulletin

Differential effects of nicotine, alcohol, and co-exposure on neuroimmune-related protein and gene expression in corticolimbic brain regions in rats

Christie Randall, Dongxiao Sun, Patrick Randall, ACS Chemical Neuroscience

Central amygdala neuroimmune signaling in alcohol use disorder

Mariam Melkumyan, Patrick A. Randall, Yuval Silberman, 2025, Addiction Neuroscience

A novel alcohol+nicotine co-use self-administration procedure reveals sex differences and differential alteration of mesocorticolimbic TLR- and cholinergic-related neuroimmune gene expression in rats

Christie A. Randall, Dongxiao Sun, Patrick A. Randall, 2024, Alcohol on p. 115-131

Adolescent alcohol disrupts development of noradrenergic neurons in the nucleus of the tractus solitarius and enhances stress behaviors in adulthood in mice in a sex specific manner

Liz A. Aguilar, Elizabeth Aguilar, Caitlin R. Coker, Yuval Silberman, Zari McCullers, Alexandra Evans, Opeyemi Showemimo, Mariam Melkumyan, Bailey N. Keller, Angela E. Snyder, Sarah S. Bingaman, Patrick A. Randall, Andras Hajnal, Kirsteen N. Browning, Amy C. Arnold, 2023, Addiction Neuroscience

Alcohol, nicotine, and COVID-19: A retrospective study of health outcomes in central Pennsylvania

Kevin Lou Xu, Patrick Arthur Randall, 2023, Journal of Electrophysiological Techniques on p. 175-183

Increased alcohol self-administration following repeated Toll-like receptor 3 agonist treatment in male and female rats

Dennis F. Lovelock, Patrick A. Randall, Kalynn Van Voorhies, Ryan P. Vetreno, Fulton T. Crews, Joyce Besheer, 2022, Pharmacology Biochemistry and Behavior

Ethanol inhibits pancreatic projecting neurons in the dorsal motor nucleus of the vagus

Bailey Keller, Patrick Randall, Kirsteen Browning, Amy Arnold, A Arnold, Kirsteen N. Browning, Yuval Silberman, 2022, Journal of Electrophysiological Techniques on p. 121-129

Differential Effects of Nicotine, Alcohol, and Coexposure on Neuroimmune-Related Protein and Gene Expression in Corticolimbic Brain Regions of Rats

Christie A. Randall, Dongxiao Sun, Patrick A. Randall, 2022, ACS Chemical Neuroscience

Low-dose alcohol: Interoceptive and molecular effects and the role of dentate gyrus in rats

Patrick Randall, D Lovelock, K VanVoorhies, V Agan, T Kash, J Besheer, 2021, Addiction Biology on p. e12965

Most-Cited Papers

Bupropion increases selection of high effort activity in rats tested on a progressive ratio/chow feeding choice procedure: Implications for treatment of effort-related motivational symptoms

Patrick A. Randall, Christie A. Lee, Samantha J. Podurgiel, Evan Hart, Samantha E. Yohn, Myles Jones, Margaret Rowland, Laura Lopez-Cruz, Merce Correa, John D. Salamone, 2015, International Journal of Neuropsychopharmacology on p. 1-11

The VMAT-2 inhibitor tetrabenazine alters effort-related decision making as measured by the T-maze barrier choice task: Reversal with the adenosine A<sub>2A</sub> antagonist MSX-3 and the catecholamine uptake blocker bupropion

S Yohn, C Thompson, Patrick Randall, C Lee, C Müller, Y Baqi, M Correa, J Salamone, 2015, Psychopharmacology on p. 1313-23

Sex differences in alcohol self-administration and relapse-like behavior in Long-Evans rats

Patrick A. Randall, Robert T. Stewart, Joyce Besheer, 2017, Pharmacology Biochemistry and Behavior on p. 1-9

Functional role for cortical-striatal circuitry in modulating alcohol self-administration

Anel A. Jaramillo, Patrick A. Randall, Spencer Stewart, Brayden Fortino, Kalynn Van Voorhies, Joyce Besheer, 2018, Neuropharmacology on p. 42-53

Silencing the insular-striatal circuit decreases alcohol self-administration and increases sensitivity to alcohol

Anel A. Jaramillo, Kalynn Van Voorhies, Patrick A. Randall, Joyce Besheer, 2018, Behavioural Brain Research on p. 74-81

The Toll-Like Receptor 3 Agonist Poly(I:C) Induces Rapid and Lasting Changes in Gene Expression Related to Glutamatergic Function and Increases Ethanol Self-Administration in Rats

Patrick A. Randall, Ryan P. Vetreno, Viren H. Makhijani, Fulton T. Crews, Joyce Besheer, 2019, Alcoholism: Clinical and Experimental Research on p. 48-60

Modulation of sensitivity to alcohol by cortical and thalamic brain regions

Anel A. Jaramillo, Patrick A. Randall, Suzanne Frisbee, Joyce Besheer, 2016, European Journal of Neuroscience on p. 2569-2580

Considering Drug-Associated Contexts in Substance Use Disorders and Treatment Development

Mandy Rita LeCocq, Patrick A. Randall, Joyce Besheer, Nadia Chaudhri, 2020, Neurotherapeutics on p. 43-54

The role of varenicline on alcohol-primed self-administration and seeking behavior in rats

Patrick A. Randall, Anel A. Jaramillo, Suzanne Frisbee, Joyce Besheer, 2015, Psychopharmacology on p. 2443-2454

Gabapentin potentiates sensitivity to the interoceptive effects of alcohol and increases alcohol self-administration in rats

Joyce Besheer, Suzanne Frisbee, Patrick A. Randall, Anel A. Jaramillo, Maria Masciello, 2016, Neuropharmacology on p. 216-224