Guohong Li

Professor of Neurosurgery

Guohong Li

Research Summary

Ischemic Stroke; Traumatic Brain Injury; Cerebral Small Vessel Disease and VCID

Huck Affiliations

Links

Most Recent Publications

J147 treatment protects against traumatic brain injury by inhibiting neuronal endoplasmic reticulum stress potentially via the AMPK/SREBP-1 pathway

Rong Jin, Min Wang, Manish Shukla, Yuguo Lei, Dong An, Jiwen Du, Guohong Li, 2024, Translational Research on p. 21-34

Emerging functions and therapeutic targets of IL-38 in central nervous system diseases

Yuan Gao, Luwei Cai, Yulu Wu, Min Jiang, Yidan Zhang, Wenjing Ren, Yirui Song, Lili Li, Ziguang Lei, Youzhuang Wu, Luwen Zhu, Jing Li, Dongya Li, Guohong Li, Chengliang Luo, Luyang Tao, 2024, CNS Neuroscience and Therapeutics

Blocking of PI3-kinase beta protects against cerebral ischemia/reperfusion injury by reducing platelet activation and downstream microvascular thrombosis in rats

Qiong Cheng, Min Wang, Rong Jin, Guohong Li, 2023, Scientific Reports

Mesenchymal stromal cells and alpha-1 antitrypsin have a strong synergy in modulating inflammation and its resolution

L Han, X Wu, O Wang, X Luan, W Velander, M Aynardi, E. Scott Halstead, A Bonavia, R Jin, G Li, Y Li, Y Wang, C Dong, Y Lei, 2023, Theranostics on p. 2843-2862

Emerging Role of MicroRNA-30c in Neurological Disorders

Manish Kumar, Guohong Li, 2023, International Journal of Molecular Sciences

J147 Reduces tPA-Induced Brain Hemorrhage in Acute Experimental Stroke in Rats

Rong Jin, Min Wang, Wei Zhong, Charles R. Kissinger, J. Ernest Villafranca, Guohong Li, 2022, Frontiers in Neurology

Inhibition of PI3Kγ by AS605240 plus low-dose tissue plasminogen activator (tPA) combination improves thrombolytic therapy in a rat model of embolic stroke

Rong Jin, Wei Zhong, Shan Liu, Min Wang, Guohong Li, 2020, Neuroscience Letters

Nanoparticle Delivery of CD147 Antagonistic Peptide-9 Protects against Acute Ischemic Brain Injury and tPA-Induced Intracerebral Hemorrhage in Mice

Shan Liu, Rong Jin, Min Wang, Guohong Li, 2020, ACS Applied Bio Materials on p. 1976-1985

Inhibition of CD147 improves oligodendrogenesis and promotes white matter integrity and functional recovery in mice after ischemic stroke

Shan Liu, Rong Jin, Adam Y. Xiao, Wei Zhong, Guohong Li, 2019, Brain, Behavior, and Immunity on p. 13-24

CD147 as a key mediator of the spleen inflammatory response in mice after focal cerebral ischemia

Rong Jin, Wei Zhong, Shan Liu, Guohong Li, 2019, Journal of Neuroinflammation

Most-Cited Papers

Tissue plasminogen activator-based nanothrombolysis for ischemic stroke

Shan Liu, Xiaozhou Feng, Rong Jin, Guohong Li, 2018, Expert Opinion on Drug Delivery on p. 173-184

Inhibition of CD147 (cluster of differentiation 147) ameliorates acute ischemic stroke in mice by reducing thromboinflammation

Rong Jin, Adam Y. Xiao, Rui Chen, D. Neil Granger, Guohong Li, 2017, Stroke on p. 3356-3365

Function of CD147 in Atherosclerosis and Atherothrombosis

Cuiping Wang, Rong Jin, Xiaolei Zhu, Jinchuan Yan, Guohong Li, 2015, Advances in Data Analysis and Classification on p. 59-66

Prospective study of fasting blood glucose and intracerebral hemorrhagic risk

Cheng Jin, Guohong Li, Kathryn M. Rexrode, Mahmut E. Gurol, Xiaodong Yuan, Ying Hui, Chunyu Ruan, Anand Vaidya, Yanxiu Wang, Shouling Wu, Xiang Gao, 2018, Stroke on p. 27-33

PI3Kγ (Phosphoinositide 3-Kinase γ) regulates vascular smooth muscle cell phenotypic modulation and neointimal formation through CREB (Cyclic AMP-Response Element binding protein)/YAP (Yes-Associated Protein) Signaling

Qihong Yu, Wei Li, Rong Jin, Shiyong Yu, Dawei Xie, Xichuan Zheng, Wei Zhong, Xiang Cheng, Shaobo Hu, Min Li, Qichang Zheng, Guohong Li, Zifang Song, 2019, Arteriosclerosis, Thrombosis, and Vascular Biology on p. e91-e105

Taurine Reduces tPA (Tissue-Type Plasminogen Activator)-Induced Hemorrhage and Microvascular Thrombosis after Embolic Stroke in Rat

Rong Jin, Adam Y. Xiao, Shan Liu, Min Wang, Guohong Li, 2018, Stroke on p. 1708-1718

Withaferin A suppresses the up-regulation of acetyl-coA carboxylase 1 and skin tumor formation in a skin carcinogenesis mouse model

Wenjuan Li, Chunjing Zhang, Hongyan Du, Vincent Huang, Brandi Sun, John P. Harris, Quitin Richardson, Xinggui Shen, Rong Jin, Guohong Li, Christopher G. Kevil, Xin Gu, Runhua Shi, Yunfeng Zhao, 2016, Molecular Carcinogenesis on p. 1739-1746

Inhibition of CD147 improves oligodendrogenesis and promotes white matter integrity and functional recovery in mice after ischemic stroke

Shan Liu, Rong Jin, Adam Y. Xiao, Wei Zhong, Guohong Li, 2019, Brain, Behavior, and Immunity on p. 13-24

Shikonin suppresses skin carcinogenesis via inhibiting cell proliferation

Wenjuan Li, Chunjing Zhang, Amy Ren, Teena Li, Rong Jin, Guohong Li, Xin Gu, Runhua Shi, Yunfeng Zhao, 2015, PLoS One

UCP2 knockout suppresses mouse skin carcinogenesis

Wenjuan Li, Chunjing Zhang, Kasey Jackson, Xingui Shen, Rong Jin, Guohong Li, Christopher G. Kevil, Xin Gu, Runhua Shi, Yunfeng Zhao, 2015, Cancer Prevention Research on p. 487-491