George Perry

Professor of Anthropology and Biology

George Perry

Research Summary

Anthropological genomics, paleogenomics, human body size evolution, parasite evolution, and evolutionary medicine.

Huck Affiliations

Links

Publication Tags

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Genome History Genes Body Size Agriculture Phenotype Population Madagascar Genomics Single Nucleotide Polymorphism Rainforest Ecology Human Behavior Human Body Chromosomes Natural Selection Lemur Gourd Extinction Farmers Temperature Primates Habitat Lemuridae Genetic Selection

Most Recent Publications

Human subsistence and signatures of selection on chemosensory genes

Carrie C. Veilleux, Eva C. Garrett, Petar Pajic, Marie Saitou, Joseph Ochieng, Lilia D. Dagsaan, Nathaniel J. Dominy, George H. Perry, Omer Gokcumen, Amanda D. Melin, 2023, Communications Biology

Applying an evolutionary mismatch framework to understand disease susceptibility

Amanda J. Lea, Andrew G. Clark, Andrew W. Dahl, Orrin Devinsky, Angela R. Garcia, Christopher D. Golden, Joseph Kamau, Thomas S. Kraft, Yvonne A.L. Lim, Dino J. Martins, Donald Mogoi, Päivi Pajukanta, George H. Perry, Herman Pontzer, Benjamin C. Trumble, Samuel S. Urlacher, Vivek V. Venkataraman, Ian J. Wallace, Michael Gurven, Daniel E. Lieberman, Julien F. Ayroles, 2023, PLoS Biology

An integrative skeletal and paleogenomic analysis of stature variation suggests relatively reduced health for early European farmers

Stephanie Marciniak, Christina M. Bergey, Ana Maria Silva, Agata Hałuszko, Mirosław Furmanek, Barbara Veselka, Petr Velemínský, Giuseppe Vercellotti, Joachim Wahl, Gunita Zariņa, Cristina Longhi, Jan Kolář, Rafael Garrido-Pena, Raúl Flores-Fernández, Ana M. Herrero-Corral, Angela Simalcsik, Werner Müller, Alison Sheridan, Žydrūnė Miliauskienė, Rimantas Jankauskas, Vyacheslav Moiseyev, Kitti Köhler, Ágnes Király, Beatriz Gamarra, Olivia Cheronet, Vajk Szeverényi, Viktória Kiss, Tamás Szeniczey, Krisztián Kiss, Zsuzsanna K. Zoffmann, Judit Koós, Magdolna Hellebrandt, Robert M. Maier, László Domboróczki, Cristian Virag, Mario Novak, David Reich, Tamás Hajdu, Noreen von Cramon-Taubadel, Ron Pinhasi, George H. Perry, 2022, Proceedings of the National Academy of Sciences of the United States of America on p. e2106743119

Potential evolutionary body size reduction in a Malagasy primate (Propithecus verreauxi) in response to human size-selective hunting pressure

Alexis Sullivan, Laurie Godfrey, Richard Lawler, Heritiana Randrianatoandro, Laurie Eccles, Brendan Culleton, Timothy Ryan, George H. Perry, 2022, American Journal of Biological Anthropology on p. 385-398

A chromosome-level genome assembly for the eastern fence lizard (Sceloporus undulatus), a reptile model for physiological and evolutionary ecology

Aundrea K. Westfall, Rory S. Telemeco, Mariana B. Grizante, Damien S. Waits, Amanda D. Clark, Dasia Y. Simpson, Randy L. Klabacka, Alexis P. Sullivan, George H. Perry, Michael W. Sears, Christian L. Cox, Robert M. Cox, Matthew E. Gifford, Henry B. John-Alder, Tracy Langkilde, Michael J. Angilletta, Adam D. Leaché, Marc Tollis, Kenro Kusumi, Tonia S. Schwartz, 2021, GigaScience

Erratum: The genomics of ecological flexibility, large brains, and long lives in capuchin monkeys revealed with fecalFACS (Proc. Natl. Acad. Sci. U.S.A. (2021) 118 (e2010632118) DOI: 10.1073/pnas.2010632118)

Joseph D. Orkin, Michael J. Montague, Daniela Tejada-Martinez, Marc de Manuel, Javier del Campo, Saul Cheves Hernandez, Anthony Di Fiore, Claudia Fontsere, Jason A. Hodgson, Mareike C. Janiak, Lukas F.K. Kuderna, Esther Lizano, Maria Pia Martin, Yoshihito Niimura, George H. Perry, Carmen Soto Valverde, Jia Tang, Wesley C. Warren, João Pedro de Magalhães, Shoji Kawamura, Tomàs Marquès-Bonet, Roman Krawetz, Amanda D. Melin, 2021, Proceedings of the National Academy of Sciences of the United States of America

Evolutionary medicine

George H. Perry, 2021, eLife

Evolutionary and phylogenetic insights from a nuclear genome sequence of the extinct, giant, “subfossil” koala lemur Megaladapis edwardsi

Stephanie Marciniak, Mehreen R. Mughal, Laurie R. Godfrey, Richard J. Bankoff, Heritiana Randrianatoandro, Brooke E. Crowley, Christina M. Bergey, Kathleen M. Muldoon, Jeannot Randrianasy, Brigitte M. Raharivololona, Stephan C. Schuster, Ripan S. Malhi, Anne D. Yoder, Edward E. Louis, Logan Kistler, George H. Perry, 2021, Proceedings of the National Academy of Sciences of the United States of America

Patterns of recent natural selection on genetic loci associated with sexually differentiated human body size and shape phenotypes

A Arner, K Grogan, M Grabowski, H Reyes-Centeno, George Perry, 2021, PLoS Genetics on p. e1009562

A common 1.6 mb Y-chromosomal inversion predisposes to subsequent deletions and severe spermatogenic failure in humans

Pille Hallast, Laura Kibena, Margus Punab, Elena Arciero, Siiri Rootsi, Marina Grigorova, Rodrigo Flores, Mark A. Jobling, Olev Poolamets, Kristjan Pomm, Paul Korrovits, Kristiina Rull, Yali Xue, Chris Tyler-Smith, Maris Laan, George H. Perry, 2021, eLife

Most-Cited Papers

Archaeogenomic evidence reveals prehistoric matrilineal dynasty

D Kennett, Stephen Plog, Richard George, Brendan Culleton, Adam Watson, Pontus Skoglund, Nadin Rohland, Swapan Mallick, Kristin Stewardson, Logan Kistler, Steven Leblanc, Peter Whiteley, David Reich, George H. Perry, 2017, Nature Communications

Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America

Etienne Patin, Marie Lopez, Rebecca Grollemund, Paul Verdu, Christine Harmant, Hélène Quach, Guillaume Laval, George H. Perry, Luis B. Barreiro, Alain Froment, Evelyne Heyer, Achille Massougbodji, Cesar Fortes-Lima, Florence Migot-Nabias, Gil Bellis, Jean Michel Dugoujon, Joana B. Pereira, Verónica Fernandes, Luisa Pereira, Lolke Van Der Veen, Patrick Mouguiama-Daouda, Carlos D. Bustamante, Jean Marie Hombert, Lluís Quintana-Murci, 2017, Science on p. 543-546

Transposable elements are the primary source of novelty in primate gene regulation

Marco Trizzino, Yo Son Park, Marcia Holsbach-Beltrame, Katherine Aracena, Katelyn Mika, Minal Caliskan, George H. Perry, Vincent J. Lynch, Christopher D. Brown, 2017, Genome Research on p. 1623-1633

Human behaviour as a long-term ecological driver of non-human evolution

Alexis P. Sullivan, Douglas W. Bird, George H. Perry, 2017, Nature Ecology and Evolution

Harnessing ancient genomes to study the history of human adaptation

Stephanie Marciniak, George H. Perry, 2017, Nature Reviews Genetics on p. 659-674

Elephantid Genomes Reveal the Molecular Bases of Woolly Mammoth Adaptations to the Arctic

Vincent J. Lynch, Oscar C. Bedoya-Reina, Aakrosh Ratan, Michael Sulak, Daniela I. Drautz-Moses, George H. Perry, Webb Miller, Stephan C. Schuster, 2015, Cell Reports on p. 217-228

Gourds and squashes (Cucurbita spp.) adapted to megafaunal extinction and ecological anachronism through domestication

Logan Kistlera, Lee A. Newsoma, Timothy M. Ryana, Andrew C. Clarke, Bruce D. Smith, George H. Perry, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. 15107-15112

The impact of agricultural emergence on the genetic history of African rainforest hunter-gatherers and agriculturalists

Etienne Patin, Katherine J. Siddle, Guillaume Laval, Hélène Quach, Christine Harmant, Noémie Becker, Alain Froment, Béatrice Régnault, Laure Lemée, Simon Gravel, Jean Marie Hombert, Lolke Van Der Veen, Nathaniel J. Dominy, George H. Perry, Luis B. Barreiro, Paul Verdu, Evelyne Heyer, Lluís Quintana-Murci, 2014, Nature Communications

Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers

George H. Perry, Matthieu Foll, Jean Christophe Grenier, Etienne Patin, Yohann Nédélec, Alain Pacis, Maxime Barakatt, Simon Gravel, Xiang Zhou, Sam L. Nsobya, Laurent Excoffier, Lluis Quintana-Murci, Nathaniel J. Dominy, Luis B. Barreiro, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. E3596-E3603

Comparative and population mitogenomic analyses of Madagascar's extinct, giant 'subfossil' lemurs

Logan Kistler, Aakrosh Ratan, Laurie R. Godfrey, Brooke E. Crowley, Cris E. Hughes, Runhua Lei, Yinqiu Cui, Mindy L. Wood, Kathleen M. Muldoon, Haingoson Andriamialison, John J. McGraw, Lynn P. Tomsho, Stephan C. Schuster, Webb Miller, Edward E. Louis, Anne D. Yoder, Ripan S. Malhi, George H. Perry, 2015, Journal of Human Evolution on p. 45-54

News Articles Featuring George Perry

Sep 21, 2023

Huck-supported graduate degree programs transition to new leadership

David Koslicki and Greg Shearer have stepped into the leadership roles for the Huck's Bioinformatics and Genomics (BG) and Physiology graduate programs.

Full Article

Jun 12, 2023

Penn State announces tenure-line faculty promotions, effective July 1, 2023

The following is a list of academic promotions for tenured and tenure-line faculty members at Penn State, effective July 1, 2023.

Full Article

Feb 21, 2023

NIH grant allows grad student to study Cuban, Cuban-American health disparities

Growing up in Miami’s Cuban American community, Margarita “Maggie” Hernandez said she often felt “like I wasn’t Cuban enough, but also not American enough.” Today, though, she’s beyond proud of her roots — so much so that she’s made it a hallmark of her research.

Full Article

Jun 30, 2022

Graduate students awarded 2022 NASA Space Grant Fellowships

Seventeen Penn State graduate students have received 2022 NASA Pennsylvania Space Grant awards and been named graduate fellows.

Full Article

Apr 07, 2022

First European farmers' heights did not meet expectations

A combined study of genetics and skeletal remains shows that the switch from primarily hunting, gathering and foraging to farming about 12,000 years ago in Europe may have had negative health effects as indicated by shorter than expected heights in the earliest farmers, according to an international team of researchers.

Full Article

Jun 22, 2021

Newly sequenced genome of extinct giant lemur sheds light on animal's biology

Using an unusually well-preserved subfossil jawbone, a team of researchers — led by Penn State and with a multi-national team of collaborators including scientists from the Université d’Antananarivo in Madagascar — has sequenced for the first time the nuclear genome of the koala lemur (Megaladapis edwardsi), one of the largest of the 17 or so giant lemur species that went extinct on the island of Madagascar between about 500 and 2,000 years ago.

Full Article

Aug 05, 2019

New Bioinformatics and Genomics Chair Looks To Capitalize on Program's Strengths

New chair George Perry is considering opportunities for expanded partnerships that will build on the solid foundations already in place in the BG program.

Full Article

May 07, 2019

Institutes of Energy and the Environment announces seed grant recipients

Several Huck researchers are among the recipients of 2018-19 IEE seed grants.

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