Gavin Robertson

Professor of Pharmacology

Gavin Robertson

Huck Affiliations

Most Recent Publications

Tumor Heterogeneity Shapes Survival Dynamics in Drug-Treated Cells, Revealing Size-Drifting Subpopulations

Venugopal Vangala, Yu Chi Chen, Saketh S. Dinavahi, Krishne Gowda, Nazir A. Lone, Meenhard Herlyn, Joseph Drabick, Klaus Helm, Jiyue Zhu, Rogerio I. Neves, Arun K. Sharma, Arthur Berg, Marco Archetti, Shantu Amin, Todd D. Schell, Gavin P. Robertson, 2024, ACS Pharmacology and Translational Science on p. 3573-3584

Identification of Novel Isatin Derivative Bearing a Nitrofuran Moiety as Potent Multi-Isoform Aldehyde Dehydrogenase Inhibitor

Krishne Gowda, Asif Raza, Venugopal Vangala, Nazir Ahmad Lone, Jyh Ming Lin, Jaikee Kumar Singh, Sandeep Kumar Srivastava, Todd D. Schell, Gavin P. Robertson, Shantu Amin, Arun K. Sharma, 2024, Molecules

Pharmacological agents targeting drug-tolerant persister cells in cancer

Yu Chi Chen, Krishne Gowda, Shantu Amin, Todd D. Schell, Arun K. Sharma, Gavin P. Robertson, 2024, Pharmacological Research

Telomere dysfunction in Tert knockout mice delays Braf<sup>V600E</sup>-induced melanoma development

Jinglong Zhang, Fan Zhang, Kenneth I. Porter, Panshak P. Dakup, Shuwen Wang, Gavin P. Robertson, Shobhan Gaddameedhi, Jiyue Zhu, 2024, International Journal of Cancer on p. 548-560

Development of a novel Bruton’s tyrosine kinase inhibitor that exerts anti-cancer activities potentiates response of chemotherapeutic agents in multiple myeloma stem cell-like cells

Weam Othman Elbezanti, Omar S. Al-Odat, Robert Chitren, Jaikee Kumar Singh, Sandeep Kumar Srivastava, Krishne Gowda, Shantu Amin, Gavin P. Robertson, Venkatesh V. Nemmara, Subash C. Jonnalagadda, Tulin Budak-Alpdogan, Manoj K. Pandey, 2022, Frontiers in Pharmacology

Drug-Tolerant Persister Cells in Cancer Therapy Resistance

Pavan Kumar Dhanyamraju, Todd D. Schell, Shantu Amin, Gavin P. Robertson, 2022, Cancer Research on p. 2503-2514

Targeting WEE1/AKT Restores p53-Dependent Natural Killer–Cell Activation to Induce Immune Checkpoint Blockade Responses in “Cold” Melanoma

Saketh S. Dinavahi, Yu Chi Chen, Kishore Punnath, Arthur Berg, Meenhard Herlyn, Momeneh Foroutan, Nicholas D. Huntington, Gavin P. Robertson, 2022, Cancer immunology research on p. 757-769

Targeting Protein Translation in Melanoma by Inhibiting EEF-2 Kinase Regulates Cholesterol Metabolism though SREBP2 to Inhibit Tumour Development

Saketh S. Dinavahi, Yu Chi Chen, Raghavendra Gowda, Pavan Kumar Dhanyamraju, Kishore Punnath, Dhimant Desai, Arthur Berg, Scot R. Kimball, Shantu Amin, Jin Ming Yang, Gavin P. Robertson, 2022, International Journal of Molecular Sciences

Polymorphic tandem DNA repeats activate the human telomerase reverse transcriptase gene

Tao Xu, De Cheng, Yuanjun Zhao, Jinglong Zhang, Xiaolu Zhu, Fan Zhang, Gang Chen, Yang Wang, Xiufeng Yan, Gavin P. Robertson, Shobhan Gaddameedhi, Philip Lazarus, Shuwen Wang, Jiyue Zhu, 2021, Proceedings of the National Academy of Sciences of the United States of America

Activating Sphingosine-1-phospahte signaling in endothelial cells increases myosin light chain phosphorylation to decrease endothelial permeability thereby inhibiting cancer metastasis

Yu Chi Chen, Saketh S. Dinavahi, Qilong Feng, Raghavendra Gowda, Srinivasa Ramisetti, Xinghai Xia, Kyle B. LaPenna, Venkat R. Chirasani, Sung Hyun Cho, Susan L. Hafenstein, Madhu Babu Battu, Arthur Berg, Arun K. Sharma, Tom Kirchhausen, Nikolay V. Dokholyan, Shantu Amin, Pingnian He, Gavin P. Robertson, 2021, Cancer Letters on p. 107-119

Most-Cited Papers

The role of cholesterol in cancer

Omer F. Kuzu, Mohammad A. Noory, Gavin P. Robertson, 2016, Cancer Research on p. 2063-2070

Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia

Chunhua Song, Chandrika Gowda, Xiaokang Pan, Yali Ding, Yongqing Tong, Bi Hua Tan, Haijun Wang, Sunil Muthusami, Zheng Ge, Mansi Sachdev, Shantu G. Amin, Dhimant Desai, Krishne Gowda, Raghavendra Gowda, Gavin P. Robertson, Hilde Schjerven, Markus Muschen, Kimberly J. Payne, Sinisa Dovat, 2015, Blood on p. 1813-1822

The role of exosomes in metastasis and progression of melanoma

Raghavendra Gowda, Bailey M. Robertson, Soumya Iyer, John Barry, Saketh S. Dinavahi, Gavin P. Robertson, 2020, Cancer Treatment Reviews

Aldehyde Dehydrogenase Inhibitors for Cancer Therapeutics

Saketh S. Dinavahi, Christopher G. Bazewicz, Raghavendra Gowda, Gavin P. Robertson, 2019, Trends in Pharmacological Sciences on p. 774-789

Nanoparticle-based celecoxib and plumbagin for the synergistic treatment of melanoma

Raghavendra Gowda, Gregory Kardos, Arati Sharma, Sanjay Singh, Gavin P. Robertson, 2017, Molecular Cancer Therapeutics on p. 440-452

Effect of lysosomotropic molecules on cellular homeostasis

Omer F. Kuzu, Mesut Toprak, M. Anwar Noory, Gavin P. Robertson, 2017, Pharmacological Research on p. 177-184

Modulating cancer cell survival by targeting intracellular cholesterol transport

Omer F. Kuzu, Raghavendra Gowda, Mohammad A. Noory, Gavin P. Robertson, 2017, British Journal of Cancer on p. 513-524

Nanotechnology-based strategies for combating toxicity and resistance in melanoma therapy

Adam K. Brys, Raghavendra Gowda, Daniel B. Loriaux, Gavin P. Robertson, Paul J. Mosca, 2016, Biotechnology Advances on p. 565-577

Drug-Tolerant Persister Cells in Cancer Therapy Resistance

Pavan Kumar Dhanyamraju, Todd D. Schell, Shantu Amin, Gavin P. Robertson, 2022, Cancer Research on p. 2503-2514

Aldehyde dehydrogenase in regulatory T-cell development, immunity and cancer

Christopher G. Bazewicz, Saketh S. Dinavahi, Todd D. Schell, Gavin P. Robertson, 2019, Immunology on p. 47-55