Darrell Cockburn

Associate Professor of Food Science

Darrell Cockburn

Huck Affiliations

Links

Publication Tags

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Starch Carbohydrates Enzymes Binding Sites Polysaccharides Glycoside Hydrolases Health Amylases Gastrointestinal Microbiome Electrophoresis Catalysis Gene Expression Mutation Cellulose Mashing Polymerization Phylogeny Bacteria Oligosaccharides Carbohydrate Sugars Butyrates Hordeum Surface Plasmon Resonance Degradation

Most Recent Publications

Clostridium butyricum Prazmowski can degrade and utilize resistant starch via a set of synergistically acting enzymes

Tara L. Pickens, Darrell W. Cockburn, 2024, mSphere

Microscopic assessment of the degradation of millet starch granules by endogenous and exogenous enzymes during mashing

Andrew Ledley, Gregory Ziegler, Ryan Elias, Darrell W. Cockburn, 2023, Carbohydrate Polymers on p. 13

Evaluating the Role of Mashing in the Amino Acid Profiles of Worts Produced from Gluten-Free Malts

Andrew J. Ledley, Ryan J. Elias, Darrell W. Cockburn, 2023, Beverages

Evaluating the efficacy of non-thermal microbial load reduction treatments of heat labile food components for in vitro fermentation experiments

Andrew Paff, Darrell W. Cockburn, 2023, PLoS One

Affinity Electrophoresis for Analysis of Catalytic Module-Carbohydrate Interactions

Darrell W. Cockburn, Casper Wilkens, Birte Svensson, 2023, Methods in Molecular Biology on p. 91-101

Surface Plasmon Resonance Analysis for Quantifying Protein-Carbohydrate Interactions

Marie Sofie Møller, Darrell W. Cockburn, Casper Wilkens, 2023, Methods in Molecular Biology on p. 141-150

Evaluating the role of mashing in the amino acid profiles of worts produced from gluten-free malts

Andrew Ledley, R Elias, Darrell Cockburn, 2023, Beverages on p. 10

Impact of mashing protocol on the formation of fermentable sugars from millet in gluten-free brewing

Andrew Ledley, R Elias, Darrell Cockburn, 2023, Food Chemistry on p. 134758

Additional Resistant Starch from One Potato Side Dish per Day Alters the Gut Microbiota but Not Fecal Short-Chain Fatty Acid Concentrations

P DeMartino, E Johnston, Kristina Petersen, Penny Kris-Etherton, Darrell W. Cockburn, 2022, Nutrients

Resistant starch: the dietary fiber of the starch world

Darrell Cockburn, 2022, on p. 197-218

Most-Cited Papers

Polysaccharide Degradation by the Intestinal Microbiota and Its Influence on Human Health and Disease

Darrell W. Cockburn, Nicole M. Koropatkin, 2016, Journal of Molecular Biology on p. 3230-3252

Resistant starch: impact on the gut microbiome and health

Peter DeMartino, Darrell W. Cockburn, 2020, Current Opinion in Biotechnology on p. 66-71

The Sus operon: a model system for starch uptake by the human gut Bacteroidetes

Matthew H. Foley, Darrell W. Cockburn, Nicole M. Koropatkin, 2016, Cellular and Molecular Life Sciences on p. 2603-2617

Molecular details of a starch utilization pathway in the human gut symbiont Eubacterium rectale

Darrell W. Cockburn, Nicole I. Orlovsky, Matthew H. Foley, Kurt J. Kwiatkowski, Constance M. Bahr, Mallory Maynard, Borries Demeler, Nicole M. Koropatkin, 2015, Molecular Microbiology on p. 209-230

Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii

Indrani Mukhopadhya, Sarah Moraïs, Jenny Laverde-Gomez, Paul O. Sheridan, Alan W. Walker, William Kelly, Athol V. Klieve, Diane Ouwerkerk, Sylvia H. Duncan, Petra Louis, Nicole Koropatkin, Darrell Cockburn, Ryan Kibler, Philip J. Cooper, Carlos Sandoval, Emmanuelle Crost, Nathalie Juge, Edward A. Bayer, Harry J. Flint, 2018, Environmental Microbiology on p. 324-336

Novel carbohydrate binding modules in the surface anchored α-amylase of Eubacterium rectale provide a molecular rationale for the range of starches used by this organism in the human gut

Darrell W. Cockburn, Carolyn Suh, Krizia Perez Medina, Rebecca M. Duvall, Zdzislaw Wawrzak, Bernard Henrissat, Nicole M. Koropatkin, 2018, Molecular Microbiology on p. 249-264

Analysis of surface binding sites (SBSs) in carbohydrate active enzymes with focus on glycoside hydrolase families 13 and 77 - a mini-review

Darrell Cockburn, Casper Wilkens, Christian Ruzanski, Susan Andersen, Jonas Willum Nielsen, Alison M. Smith, Robert A. Field, Martin Willemoës, Maher Abou Hachem, Birte Svensson, 2014, Biologia (Poland) on p. 705-712

Surface binding sites in amylase have distinct roles in recognition of starch structure motifs and degradation

Darrell Cockburn, Morten M. Nielsen, Camilla Christiansen, Joakim M. Andersen, Julie B. Rannes, Andreas Blennow, Birte Svensson, 2015, International Journal of Biological Macromolecules on p. 338-345

In vitro Fermentation Reveals Changes in Butyrate Production Dependent on Resistant Starch Source and Microbiome Composition

June Teichmann, Darrell W. Cockburn, 2021, Frontiers in Microbiology

An efficient arabinoxylan-debranching α-l-arabinofuranosidase of family GH62 from Aspergillus nidulans contains a secondary carbohydrate binding site

Casper Wilkens, Susan Andersen, Bent O. Petersen, An Li, Marta Busse-Wicher, Johnny Birch, Darrell Cockburn, Hiroyuki Nakai, Hans E.M. Christensen, Birthe B. Kragelund, Paul Dupree, Barry McCleary, Ole Hindsgaul, Maher Abou Hachem, Birte Svensson, 2016, Applied Microbiology and Biotechnology on p. 6265-6277

News Articles Featuring Darrell Cockburn

Nov 13, 2024

This 2-step hack to reduce the calories in white rice is going viral — and dietitians say it actually works

White rice can be part of a healthy diet, but it's not the most nutritious grain out there. That's why a hack meant to reduce the calories and carbs in white rice is getting widely shared on social media.

Full Article

Feb 24, 2023

Processing, like fermentation and roasting, doesn’t cut cocoa’s health benefits

It is widely believed that when foods undergo processing, their health benefits are reduced. But that is not true for cocoa, according to a Penn State-led team of researchers, who conducted a new study using a mouse model.

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Sep 24, 2020

Penn State Microbiome Center elects new executive committee

The Penn State Microbiome Center in the Huck Institutes of the Life Sciences recently elected six new members to join its executive committee. The new members, along with 11 others who remained on the committee, started their two-year term in July.

Full Article

Jan 05, 2020

5 Things You Can Do to Make Your Microbiome Healthier

Fresh fruits and vegetables are good for you and your gut microbes

Full Article

Jan 03, 2020

5 Things You Can Do To Make Your Microbiome Healthier

Fresh fruits and vegetables are good for you and your gut microbes.

Full Article

Jan 03, 2020

5 Things That Will Help Keep Your Microbiome Healthy

A healthy diet and lifestyle will help keep your gut microbes — and you — happy.

Full Article