Arun Sharma

Associate Professor of Pharmacology

Arun Sharma

Huck Affiliations

Most Recent Publications

Altering phosphorylation in cancer through PP2A modifiers

Hannah Johnson, Satya Narayan, Arun K. Sharma, 2024, Cancer Cell International

Nutraceuticals target androgen receptor-splice variants (AR-SV) to manage castration resistant prostate cancer (CRPC)

Ashish Tyagi, Balaji Chandrasekaran, Vaibhav Shukla, Neha Tyagi, Arun K. Sharma, Chendil Damodaran, 2024, Pharmacology and Therapeutics, Part A: Chemotherapy, Toxicology and

Exploring Novel Coumarin-Tethered Bis-Triazoles: Apoptosis Induction in Human Pancreatic Cancer Cells, Antimicrobial Effects, and Molecular Modelling Investigations

Sanjeev Dhawan, Ashona Singh, Neha Manhas, Pule Seboletswe, Lungisani Khubone, Gobind Kumar, Sreekantha B. Jonnalagadda, Asif Raza, Arun K. Sharma, Parvesh Singh, 2024, Farmaco

Tumor Heterogeneity Shapes Survival Dynamics in Drug-Treated Cells, Revealing Size-Drifting Subpopulations

Venugopal Vangala, Yu Chen, Saketh Dinavahi, Krishne Gowda, Nazir Lone, Meenhard Herlyn, Joseph Drabick, Klaus Helm, J Zhu, R Neves, Arun K. Sharma, Arthur Berg, Marco Archetti, S Amin, Todd D. Schell, Gavin P. Robertson, 2024, ACS Pharmacology and Translational Science on p. 3573-3584

RNA Binding Proteins as Potential Therapeutic Targets in Colorectal Cancer

Vikash Singh, Amandeep Singh, Alvin John Liu, Serge Y. Fuchs, Arun Sharma, Vladimir S. Spiegelman, 2024, Cancers

Rational Design and Synthesis of Isatin-Chalcone Hybrids Integrated with 1H-1,2,3-Triazole: Anti-Proliferative Profiling and Molecular Docking Insights

Swati, Asif Raza, Shefali Chowdhary, Amit Anand, Shaveta, Arun K. Sharma, Kewal Kumar, Vipan Kumar, 2024, Farmaco

Identification of Novel Isatin Derivative Bearing a Nitrofuran Moiety as Potent Multi-Isoform Aldehyde Dehydrogenase Inhibitor

Krishne Gowda, Asif Raza, Venugopal Vangala, Nazir Ahmad Lone, Jyh Ming Lin, Jaikee Kumar Singh, Sandeep Kumar Srivastava, Todd D. Schell, Gavin P. Robertson, Shantu Amin, Arun K. Sharma, 2024, Molecules

Following the Trace of Cyclodextrins on the Selenium and Tellurium Odyssey

Cristina Morán-Serradilla, Daniel Plano, Arun K. Sharma, Carmen Sanmartín, 2024, International Journal of Molecular Sciences

Selenization of Small Molecule Drugs: A New Player on the Board

Cristina Morán-Serradilla, Daniel Plano, Carmen Sanmartín, Arun K. Sharma, 2024, Journal of Medicinal Chemistry on p. 7759-7787

Pharmacological agents targeting drug-tolerant persister cells in cancer

Yu Chi Chen, Krishne Gowda, Shantu Amin, Todd D. Schell, Arun K. Sharma, Gavin P. Robertson, 2024, Pharmacological Research

Most-Cited Papers

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

James C. Glasbey, Dmitri Nepogodiev, Joana F.F. Simoes, Omar Omar, Elizabeth Li, Mary L. Venn, Mohammad K.Abou Chaar, Vita Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G. Edwards, Jonathan P. Evans, Marco Fiore, Jose Flavio Videria, Samuel J. Ford, Ian Ganly, Ewen A. Griffiths, Rohan R. Gujjuri, Angelos G. Kolias, Haytham M.A. Kaafarani, Ana Minaya-Bravo, Siobhan C. McKay, Helen M. Mohan, Keith J. Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil J. Smart, Grant D. Stewart, Sudha Sundar, Raghavan Vidya, Aneel A. Bhangu, C. Allemand, L. Boccalatte, M. Figari, M. Lamm, J. Larrañaga, C. Marchitelli, F. Noll, D. Odetto, M. Perrotta, J. Saadi, L. Zamora, C. Alurralde, E. L. Caram, D. Eskinazi, J. P. Mendoza, M. Usandivaras, R. Badra, A. Esteban, 2021, Journal of Clinical Oncology on p. 66-78

Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents

Daniel Plano, Deepkamal N. Karelia, Manoj K. Pandey, Julian E. Spallholz, Shantu Amin, Arun K. Sharma, 2016, Journal of Medicinal Chemistry on p. 1946-1959

A Review on Notch Signaling and Colorectal Cancer

Ashish Tyagi, Arun K. Sharma, Chendil Damodaran, 2020, Cells

Development and Therapeutic Potential of Selenazo Compounds

Ana Carolina Ruberte, Carmen Sanmartin, Carlos Aydillo, Arun K. Sharma, Daniel Plano, 2020, Journal of Medicinal Chemistry on p. 1473-1489

Therapeutics Targeting p53-MDM2 Interaction to Induce Cancer Cell Death

Nayeong Koo, Arun K. Sharma, Satya Narayan, 2022, International Journal of Molecular Sciences

Novel seleno- and thio-urea derivatives with potent in vitro activities against several cancer cell lines

Verónica Alcolea, Daniel Plano, Deepkamal N. Karelia, Juan Antonio Palop, Shantu Amin, Carmen Sanmartín, Arun Sharma, 2016, CHIM.THER. on p. 134-144

Bolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile

John P. Hegarty, Jacek Krzeminski, Arun K. Sharma, Diana Guzman-Villanueva, Volkmar Weissig, David B. Stewart, 2016, International Journal of Nanomedicine on p. 3607-3619

Small molecule inhibitor of Igf2bp1 represses Kras and a pro-oncogenic phenotype in cancer cells

Nadav Wallis, Froma Oberman, Khriesto Shurrush, Nicolas Germain, Gila Greenwald, Tehila Gershon, Talia Pearl, Giancarlo Abis, Vikash Singh, Amandeep Singh, Arun K. Sharma, Haim M. Barr, Andres Ramos, Vladimir S. Spiegelman, Joel K. Yisraeli, 2022, RNA Biology on p. 26-43

Chalcogen containing heterocyclic scaffolds: New hybrids with antitumoral activity

Verónica Alcolea, Daniel Plano, Ignacio Encío, Juan Antonio Palop, Arun K. Sharma, Carmen Sanmartín, 2016, CHIM.THER. on p. 407-418

The apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines

Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong Gang Wang, Jong K. Yun, 2015, Journal of Pharmacology and Experimental Therapeutics on p. 494-508