Amir Sheikhi

Huck Early Career Chair in Biomaterials and Regenerative Engineering ; Associate Professor of Chemical Engineering

Amir Sheikhi

Research Summary

Micro- and nanoengineered soft materials for medicine and the environment; microfluidic-enabled biomaterials for tissue engineering and regeneration; living materials; next-generation bioadhesives, tissue sealants, and hemostatic agents; hydrogels for minimally invasive medical technologies; self-healing and adaptable soft materials; smart coatings; hairy nanocelluloses as an emerging family of advanced materials.

Huck Affiliations

Links

Publication Tags

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Hydrogels Cellulose Nanocellulose Proteins Gelatin Tissue Microfluidics Hydrogel Adsorption Silicones Aerogels Sensors Polymers Biomaterial Bone Biocompatible Materials Nanoparticles Biomaterials Porosity Application Green Costs Structural Analysis Chitosan Therapeutics

Most Recent Publications

Upcycling plastic waste into fully recyclable composites through cold sintering

Po Hao Lai, Shelby L. Hall, Yi Chen Lan, Jia Ruey Ai, Arian Jaberi, Amir Sheikhi, Rui Shi, Bryan D. Vogt, Enrique D. Gomez, 2024, Materials Horizons on p. 2718-2728

Accelerating Patterned Vascularization Using Granular Hydrogel Scaffolds and Surgical Micropuncture

Zaman Ataie, Summer Horchler, Arian Jaberi, Srinivas V. Koduru, Jessica C. El-Mallah, Mingjie Sun, Sina Kheirabadi, Alexander Kedzierski, Aneesh Risbud, Angelo Roncalli Alves E. Silva, Dino J. Ravnic, Amir Sheikhi, 2024, Small

Chemical structure–property relationships in nanocelluloses

Mica L. Pitcher, Roya Koshani, Amir Sheikhi, 2024, Journal of Polymer Science on p. 9-31

Iron inhibits glioblastoma cell migration and polarization

Ganesh Shenoy, Sina Kheirabadi, Zaman Ataie, Aurosman Pappus Sahu, Kondaiah Palsa, Quinn Wade, Chachrit Khunsriraksakul, Vladimir Khristov, Becky Slagle-Webb, Justin D. Lathia, Hong Gang Wang, Amir Sheikhi, James R. Connor, 2023, FASEB Journal

Iron inhibits glioblastoma cell migration and polarization

Ganesh Shenoy, Sina Kheirabadi, Zaman Ataie, Aurosman Pappus Sahu, Kondaiah Palsa, Quinn Wade, Chachrit Khunsriraksakul, Vladimir Khristov, Becky Slagle-Webb, Justin Lathia, Hong-Gang Wang, Amir Sheikhi, James Connor, 2023, Federation of American Societies for Experimental Biology (FASEB)

Tissue adhesive hemostatic microneedle arrays for rapid hemorrhage treatment

Reihaneh Haghniaz, Han Jun Kim, Hossein Montazerian, Avijit Baidya, Maryam Tavafoghi, Yi Chen, Yangzhi Zhu, Solmaz Karamikamkar, Amir Sheikhi, Ali Khademhosseini, 2023, Bioactive Materials on p. 314-327

Colloidal aspects of calcium carbonate scaling in water-in-oil emulsions: A fundamental study using droplet-based microfluidics

Shang Lin Yeh, Roya Koshani, Amir Sheikhi, 2023, Journal of Colloid and Interface Science on p. 536-545

Nanoengineering the Redispersibility of Cellulose Nanocrystals

Breanna Huntington, Mica L. Pitcher, Amir Sheikhi, 2023, Biomacromolecules on p. 43-56

Injectable, Antibacterial, and Hemostatic Tissue Sealant Hydrogels

Reihaneh Haghniaz, Hossein Montazerian, Atiya Rabbani, Avijit Baidya, Brent Usui, Yangzhi Zhu, Maryam Tavafoghi, Fazli Wahid, Han Jun Kim, Amir Sheikhi, Ali Khademhosseini, 2023, Advanced healthcare materials

Dynein-Powered Cell Locomotion Guides Metastasis of Breast Cancer

Yerbol Tagay, Sina Kheirabadi, Zaman Ataie, Rakesh Singh, Olivia Prince, Ashley Nguyen, Alexander Zhovmer, Xuefei Ma, Amir Sheikhi, Denis Tsygankov, Erdem Tabdanov, 2023, Advanced Science on p. 25

Most-Cited Papers

Sutureless repair of corneal injuries using naturally derived bioadhesive hydrogels

Ehsan Shirzaei Sani, Ahmad Kheirkhah, Devyesh Rana, Zhongmou Sun, William Foulsham, Amir Sheikhi, Ali Khademhosseini, Reza Dana, Nasim Annabi, 2019, Science advances

Advancing Frontiers in Bone Bioprinting

Nureddin Ashammakhi, Anwarul Hasan, Outi Kaarela, Batzaya Byambaa, Amir Sheikhi, Akhilesh K. Gaharwar, Ali Khademhosseini, 2019, Advanced healthcare materials

Status and future scope of plant-based green hydrogels in biomedical engineering

Reza Mohammadinejad, Hajar Maleki, Eneko Larrañeta, André R. Fajardo, Amirala Bakhshian Nik, Amin Shavandi, Amir Sheikhi, Mansour Ghorbanpour, Mehdi Farokhi, Praveen Govindh, Etienne Cabane, Susan Azizi, Amir Reza Aref, Masoud Mozafari, Mehdi Mehrali, Sabu Thomas, João F. Mano, Yogendra Kumar Mishra, Vijay Kumar Thakur, 2019, Applied Materials Today on p. 213-246

3D-Printed Ultra-Robust Surface-Doped Porous Silicone Sensors for Wearable Biomonitoring

Elham Davoodi, Hossein Montazerian, Reihaneh Haghniaz, Armin Rashidi, Samad Ahadian, Amir Sheikhi, Jun Chen, Ali Khademhosseini, Abbas S. Milani, Mina Hoorfar, Ehsan Toyserkani, 2020, ACS Nano on p. 1520-1532

Structural analysis of photocrosslinkable methacryloyl-modified protein derivatives

Kan Yue, Xiuyu Li, Karsten Schrobback, Amir Sheikhi, Nasim Annabi, Jeroen Leijten, Weijia Zhang, Yu Shrike Zhang, Dietmar W. Hutmacher, Travis J. Klein, Ali Khademhosseini, 2017, Biomaterials on p. 163-171

Reusable Green Aerogels from Cross-Linked Hairy Nanocrystalline Cellulose and Modified Chitosan for Dye Removal

Han Yang, Amir Sheikhi, Theo G.M. Van De Ven, 2016, Langmuir on p. 11771-11779

Minimally Invasive and Regenerative Therapeutics

Nureddin Ashammakhi, Samad Ahadian, Mohammad Ali Darabi, Mario El Tahchi, Junmin Lee, Kasinan Suthiwanich, Amir Sheikhi, Mehmet R. Dokmeci, Rahmi Oklu, Ali Khademhosseini, 2019, Advanced Materials

Microfluidic-enabled bottom-up hydrogels from annealable naturally-derived protein microbeads

Amir Sheikhi, Joseph de Rutte, Reihaneh Haghniaz, Outman Akouissi, Alireza Sohrabi, Dino Di Carlo, Ali Khademhosseini, 2019, Biomaterials on p. 560-568

Hairy cellulose nanocrystalloids: A novel class of nanocellulose

Theo G.M. Van De Ven, Amir Sheikhi, 2016, Nanoscale on p. 15101-15114

Copper removal using electrosterically stabilized nanocrystalline cellulose

Amir Sheikhi, Salman Safari, Han Yang, Theo G.M. Van De Ven, 2015, ACS applied materials & interfaces on p. 11301-11308

News Articles Featuring Amir Sheikhi

Mar 05, 2024

Combining novel biomaterial and microsurgery might enable faster tissue recovery

To speed up the formation and patterning of new blood vessels, Penn State researchers have combined a novel biomaterial with a microsurgical approach used in reconstructive surgery, enabling improved recovery of soft tissue.

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Dec 08, 2023

Penn State professors make advancements in study of breast cancer

A study unveiled findings from collaborative research conducted on the issue of metastasis within breast cancer patients

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Nov 08, 2023

NIH diversity grant to fund student’s 3D bioprinting research

Angie Castro will be supported by an NIH grant for her work on 3D printing granular scaffolds for tissue engineering and regeneration to meet precise medical needs.

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Oct 30, 2023

Protein found to control breast cancer metastasis

Scientists have discovered the motor protein dynein commands movement of cancer cells in soft tissue models, offering new clinical targets

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Oct 30, 2023

Potential New Therapeutic Target for Metastatic Breast Cancer Discovered

New research led by Penn State researchers has shown, for the first time, the mechanics of how breast cancer cells invade healthy tissues and lead to metastatic disease

Full Article

Oct 29, 2023

Research says blocking a motor protein can stop breast cancer cells

But what if there was ? to stop breast cancer cells from moving and invading healthy tissues

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Oct 29, 2023

Protein discovery could be used to stop breast cancer in its tracks

Researchers have uncovered the mechanism by which a protein facilitates the spread of breast cancer cells from the primary tumor into healthy tissue

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Oct 27, 2023

Mechanics of breast cancer metastasis discovered, offering target for treatment

New research led by Penn State reveals for the first time the mechanics behind how breast cancer cells may invade healthy tissues recently published in the journal Advanced Science.

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Aug 22, 2023

One Health Microbiome Center's 2023-24 Interdisciplinary Innovation Fellows

The One Health Microbiome Center (OHMC) in the Huck Institutes of the Life Sciences at Penn State has named five recipients for its 2023-24 Interdisciplinary Innovation Fellowships (IIF) program.

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Aug 09, 2023

Mussels inspire an eco-friendly way to extract critical rare earth elements

Rare earth elements play a key role in clean energy, vital to the production of lightweight, efficient batteries and essential components in wind turbines.

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Jul 06, 2023

Soft tissue restoration, blood vessel formation focus of $3M grant

The ability to regenerate and pattern blood vessels, the literal lifelines extending deep into soft tissues, remains an elusive milestone in regenerative medicine.

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Jan 20, 2023

Novel microneedle bandage could save lives by stopping blood loss from wounds

A soldier suffers a serious gunshot wound on a remote battlefield or a machinist has a work accident and gets stuck in traffic on the way to the hospital.

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Jan 11, 2023

Researchers uncover mechanisms to easily dry, redisperse cellulose nanocrystals

Cellulose nanocrystals — bio-based nanomaterials derived from natural resources such as plant cellulose — are valuable for their use in water treatment, packaging, tissue engineering, electronics, antibacterial coatings and much more.

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Dec 22, 2022

2022 Top 10 Most Popular Microbiome Center News Articles

The stories that made the year in 2022 for the Penn State Microbiome Center

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Nov 21, 2022

Materials Research Institute names 2022 Roy Award Winners

Seven Penn State materials researchers have received the 2022 Rustum and Della Roy Innovation in Materials Research Award.

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Nov 15, 2022

FDA-approved cholesterol medicine may help prevent antibiotic resistance

Antimicrobial resistance, including bacteria that have evolved to defy antibiotics, is one of the top 10 global public health threats humanity faces, according to the World Health Organization.

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Aug 24, 2022

New granular hydrogel bioink could expand possibilities for tissue bioprinting

Every day in the United States, 17 people die waiting for an organ transplant, and every nine minutes, another person is added to the transplant waiting list, according to the Health Resources and Services Administration.

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Aug 18, 2022

Compost to computer: Bio-based materials used to salvage rare earth elements

Penn State researchers used micro- and nanoparticles created from the organic materials to capture rare earth elements from aqueous solutions.

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Jun 06, 2022

Scientists devise method to help prevent hospital infections

On any given day, one in 31 hospital patients is diagnosed with an infection that developed as a result of care during their hospital stay, according to the Centers for Disease Control and Prevention. Medical devices such as catheters, stents, heart valves and pacemakers, whose surfaces can become covered with harmful bacterial films, account for about a quarter of such infections. To help prevent such infections, a research team led by Penn State and the University of California, Los Angeles, developed a novel surface treatment for these devices.

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