News

Apr 16, 2025

Immune system proteins involved in severe parasitic disease identified

New insights into the mechanisms that cause more severe cases of schistosomiasis — a disease caused by parasitic worms and second only to malaria in terms of potential harm — have been revealed by researchers at Penn State.

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Mar 14, 2025

Plant biologist awarded the Masatoshi Nei Innovation Prize in Biology

Sarah Assmann, Waller Professor of Plant Biology at Penn State, has been awarded the Masatoshi Nei Innovation Prize in Biology. The award was established through a generous gift from Masatoshi Nei, professor emeritus of biology at Penn State; Laura Carnell, professor of biology at Temple University; and Nei’s wife, Nobuko Nei. The prize is intended to recognize a preeminent scientist who is on the faculty at Penn State, is an innovator in their field, and has achieved outstanding scientific research and leadership in the biological sciences.

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Director Bruce Logan, fourth from left, stands with the IEE Research Award winners. From left to right are: Hong Wu, Lisa Emili, Nathaniel Warner, Brian Fronk and Margaret Busse. Lauren McPhillips is not pictured. Credit: Brenna Buck. All Rights Reserved.

Jan 28, 2025

Researchers recognized for excellence by Institute of Energy and the Environment

The Institute of Energy and the Environment recognized six Penn State faculty members for their research excellence.

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The Penn State Neuroscience community kicked off their 2024-25 seminar series with presentations by the second-year doctoral students in the Huck Neuroscience Program. The 2024 Big 10 Neuroscience Annual Meeting will provide similar events for student presentations and networking and will feature presentations from all career stages. Credit: Dan Levy and Keith Hickey/Huck Institutes. All Rights Reserved.

Jan 06, 2025

Fourth annual Big Ten Neuroscience Symposium to convene at Penn State

The Penn State Neuroscience Institute, through the Huck Institutes of the Life Sciences and the Penn State College of Medicine, will host the Big Ten Neuroscience Annual Meeting on July 21 and 22 at the Nittany Lion Inn in State College.

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New research finds sex-specific regions of the brain can relieve the detrimental effects of chronic stress in male and female mice. Left: Schematic showing a cortical microcircuit with three types of interneurons expressing somatostatin (SST), parvalbumin (PV) or vasointestinal peptide (VIP) and their distinct patterns of innervation of glutamatergic output neurons (PNs), with thin lines representing axons that send chemical signals and the thicker lines of PNs representing dendrites that receive information. There is selective innervation of the distal ends of PN dendrites by axons of SST neurons. Right: Increased activity of SST neurons by genetically induced disinhibition, on top right, or by chemogenetic activation of SST neurons in the medial prefrontal cortex, on bottom right, leads to stress resilience and facilitates the reversal of the detrimental behavioral effects of stress exposure in male but not female mice. Credit: Bernhard Lüscher / Penn State. Creative Commons

Dec 17, 2024

Brain regions that relieve effects of chronic stress in mice differ based on sex

In two new studies, researchers made mice resilient to stress by activating neurons in different brain regions and found that the changes involved are highly sex-specific

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Dec 12, 2024

Relieving chronic stress in the brains of male and female mice

In two new studies, researchers made mice resilient to stress by activating neurons in different brain regions and show that the brain regions and gene expression changes involved are highly sex-specific.

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Nov 14, 2024

Three Penn State researchers awarded scientific grants from Kaufman Foundation

The Charles E. Kaufman Foundation — a supporting organization of The Pittsburgh Foundation, which works to improve the quality of life in the Pittsburgh region — has selected three Penn State researchers to receive scientific research grants. The foundation awards grants to scientists at institutes of higher learning in Pennsylvania who are conducting innovative, fundamental scientific research in the fields of biology, chemistry and physics.

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New experimental technique developed by Penn State researchers helps uncover how certain proteins cooperate to bind to otherwise closed regions of the genome to facilitate cell differentiation and development. Illustration shows expanded view of chromosome from a cell at the upper left. The “pioneer factor” FOXA1 co-binds with AP-1, allowing FOXA1 to locate target sites in the genome with high specificity. Credit: Holly Godin/Bai Laboratory / Penn State.

Sep 11, 2024

Genomic pioneers collaborate to access the inaccessible

A new experimental method allows researchers to dissect how certain proteins, called pioneer factors, can bind to selective regions of the genome that are inaccessible to other DNA binding proteins.

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Aug 22, 2024

Cancer drug could treat early-stage Alzheimer’s disease, study shows

A type of drug developed for treating cancer holds promise as a new treatment for neurodegenerative diseases such as Alzheimer’s, according to a recent study by researchers at Penn State, Stanford University and an international team of collaborators.

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Aug 13, 2024

Rewriting the evolutionary history of critical components of the nervous system

A new study has rewritten the conventionally understood evolutionary history of certain proteins critical for electrical signaling in the nervous system. The study, led by Penn State researchers, shows that the well-studied family of proteins — potassium ion channels in the Shaker family — were present in microscopic single cell organisms well before the common ancestor of all animals.

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