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In his research, Xiaogang Hu, Dorothy Foehr Huck and J. Lloyd Huck Chair in Neurorehabilitation and an associate professor of mechanical engineering at Penn State, focuses on creating wearable assistive robotic systems for people with limited use of their limbs, especially their hands, with the goal of the user intuitively controlling the systems and devices on which they rely. Credit: Kate Myers/Penn State. All Rights Reserved.

Dec 17, 2024

Person-centered, bio-inspired research leads to improved control of prosthetics

Penn State researcher focuses on creating wearable assistive robotic systems for people with limited use of their limbs, especially their hands, with the goal of the user intuitively controlling the systems and devices on which they rely.

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New research finds sex-specific regions of the brain can relieve the detrimental effects of chronic stress in male and female mice. Left: Schematic showing a cortical microcircuit with three types of interneurons expressing somatostatin (SST), parvalbumin (PV) or vasointestinal peptide (VIP) and their distinct patterns of innervation of glutamatergic output neurons (PNs), with thin lines representing axons that send chemical signals and the thicker lines of PNs representing dendrites that receive information. There is selective innervation of the distal ends of PN dendrites by axons of SST neurons. Right: Increased activity of SST neurons by genetically induced disinhibition, on top right, or by chemogenetic activation of SST neurons in the medial prefrontal cortex, on bottom right, leads to stress resilience and facilitates the reversal of the detrimental behavioral effects of stress exposure in male but not female mice. Credit: Bernhard Lüscher / Penn State. Creative Commons

Dec 17, 2024

Brain regions that relieve effects of chronic stress in mice differ based on sex

In two new studies, researchers made mice resilient to stress by activating neurons in different brain regions and found that the changes involved are highly sex-specific

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Dec 16, 2024

Two Huck graduate students receive American Heart Association fellowships

Two Huck graduate students awarded individual 2-year American Heart Association fellowships.

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Dec 12, 2024

Center for Socially Responsible AI awards seed funding to seven diverse projects

The Penn State Center for Socially Responsible Artificial Intelligence (CSRAI) has announced the results of its most recent seed-funding competition.

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Dec 12, 2024

Relieving chronic stress in the brains of male and female mice

In two new studies, researchers made mice resilient to stress by activating neurons in different brain regions and show that the brain regions and gene expression changes involved are highly sex-specific.

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Through studies on rats, a team of researchers at Penn State has pinpointed the exact moment of loss of consciousness due to anesthesia, mapping what happens in different brain regions during that moment. Credit: Provided by Nanyin Zhang . All Rights Reserved.

Dec 11, 2024

Brain mechanisms underpinning loss of consciousness identified

Rapid activity in three brain regions appears to trigger loss of consciousness, researchers at Penn State find.

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New research shows that binge drinking in early adult mice can lead to long-lasting and potentially permanent dysregulation in the brain. The researchers used patch-clamp electrophysiology, shown here, to understand how signaling in the brain was impacted by alcohol after a long period of abstinence. Credit: Kelby Hochreither / Penn State. Creative Commons

Nov 20, 2024

Early adult binge drinking has lasting impact on aging brain in mice

Binge drinking in early adults can lead to long-lasting and potentially permanent dysregulation in the brain, according to a new study in mice, led by researchers at Penn State.

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Nov 13, 2024

Neuroscience student wins National Research Service Award fellowship

Chad Brunswick, a Ph.D candidate in the Huck Institutes’ intercollege graduate degree program in Neuroscience, has been awarded a prestigious National Research Service Award (NRSA) from the National Institute on Aging, one of the constituent institutes of the National Institutes of Health (NIH).

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Nov 14, 2024

Three Penn State researchers awarded scientific grants from Kaufman Foundation

The Charles E. Kaufman Foundation — a supporting organization of The Pittsburgh Foundation, which works to improve the quality of life in the Pittsburgh region — has selected three Penn State researchers to receive scientific research grants. The foundation awards grants to scientists at institutes of higher learning in Pennsylvania who are conducting innovative, fundamental scientific research in the fields of biology, chemistry and physics.

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Nov 20, 2024

Consistent bedtime linked with better child emotion and behavior regulation

Sleep can affect a child’s attitude and behavior, as many parents can attest, but a consistent bedtime may be more influential than sleep quality or duration, according to a new publication authored by researchers in the Penn State College of Health and Human Development and Penn State College of Medicine.

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