Molecular Cellular And Integrative Biosciences News | Molecular, Cellular, and Integrative Biosciences

Through studies on rats, a team of researchers at Penn State has pinpointed the exact moment of loss of consciousness due to anesthesia, mapping what happens in different brain regions during that moment. Credit: Provided by Nanyin Zhang . All Rights Reserved.

Dec 11, 2024

Brain mechanisms underpinning loss of consciousness identified

Rapid activity in three brain regions appears to trigger loss of consciousness, researchers at Penn State find.

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Inhye Kim, an assistant research professor of biomedical engineering at Penn State, works in the lab at the Chemical and Biomedical Engineering Building at University Park. Credit: Poornima Tomy/Penn State. All Rights Reserved.

Dec 09, 2024

Tracking immune cell brain cancer therapies with ultrasound

National Cancer Institute awards biomedical engineering researchers $3.2M to study immune cell-based cancer treatment.

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Aditya Sapre, a doctoral student studying chemical engineering, participates in the 2024 Three Minute Thesis competition. Sapre would go on to take home first place at the Penn State competition last spring. Credit: Jillian Wesner / Fox Graduate School at Penn State. All Rights Reserved.

Dec 06, 2024

Finalists named for Penn State 2024-25 Three Minute Thesis competition

Ten graduate students from eight academic programs have been named finalists for the 2024-25 Penn State Three Minute Thesis (3MT) competition.

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Penn State and U.S. National Science Foundation representatives cut a ribbon celebrating the official launch of the U.S. National Science Foundation National Synthesis Center for Emergence in the Molecular and Cellular Sciences (NCEMS) with the Penn State Nittany Lion mascot. The NCEMS launch took place on Monday, Nov. 18, and provided information about open calls for working groups, fellowships and internships, as well as a growth trajectory over the next five years. Credit: Keith Hickey/Huck Institutes. All Rights Reserved.

Dec 02, 2024

Heard on Campus: Launch of new center in molecular and cellular sciences, NCEMS

Reception celebrates new NSF-funded National Synthesis Center for Emergence in the Molecular and Cellular Sciences at Penn State.

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Xiaojun “Lance” Lian, associate professor of biomedical engineering and of biology at Penn State, will work on generating universal donor stem cells through genome editing of pluripotent stem cells in his lab. Credit: Kate Myers/Penn State. All Rights Reserved.

Nov 27, 2024

$2.6M grant to advance potential stem cell-based heart disease treatment

Combining stem cells and silicon nanowires in lab-grown tissue has shown promise as a step toward a new treatment for heart disease, the leading cause of death worldwide, according to a multi-institutional research team.

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Nov 15, 2024

Q&A: How do microbiomes influence the study of life?

Microorganisms — bacteria, viruses and other tiny life forms — may drive biological variation in visible life as much, if not more, than genetic mutations, creating new lineages and even new species of animals and plants, according to Seth Bordenstein, director of Penn State’s One Health Microbiome Center within the Huck Institutes of the Life Sciences.

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Nov 14, 2024

Three Penn State researchers awarded scientific grants from Kaufman Foundation

The Charles E. Kaufman Foundation — a supporting organization of The Pittsburgh Foundation, which works to improve the quality of life in the Pittsburgh region — has selected three Penn State researchers to receive scientific research grants. The foundation awards grants to scientists at institutes of higher learning in Pennsylvania who are conducting innovative, fundamental scientific research in the fields of biology, chemistry and physics.

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Nov 12, 2024

Uncharted territory: A Q&A with Nanyin Zhang on mapping brain activity

To understand how different regions of the brain work together, researchers use a method called resting-state functional magnetic resonance imaging (rsfMRI). The method measures brain activity by observing changes in blood flow to different parts of the brain; however, rsfMRI does not explain how these blood flow changes to different brain regions relate to what is happening with the brain’s neurons — cells that send and receive messages in the form of electronic signals.

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The novel Cleavage High-throughput Assay (CHiTA) developed at Penn State provides a scarless method to characterize thousands of diverse small self-cleaving RNA enzymes, called twister ribozymes, in a single experiment. The image shows 2D models of some of the tested ribozymes that had imperfections in their helical and loop elements but were still active, demonstrating that twister ribozyme's ability to self-cleave is tolerant of these slight structural imperfections. Credit: Lauren McKinley and Philip Bevilacqua / Penn State. Creative Commons

Nov 06, 2024

Testing thousands of RNA enzymes helps find first ‘twister ribozyme’ in mammals

A new method, developed by Penn State researchers, can test the activity of thousands of predicted ribozymes in a single experiment.

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Oct 31, 2024

Huck researchers reflect on the 2024 Nobel Prize in Chemistry

This month, the Nobel Prize in Chemistry was awarded to three scientists credited with historic breakthroughs surrounding proteins and their structures. Three Huck researchers working on similar challenges chime in with their thoughts.

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