News

Credit: Brennan Dincher / Penn State.

Three projects receive Huck Innovative and Transformational Seed Fund grants

Three potentially high-impact, high-risk research projects have been selected to receive seed funding for the latest round of the Huck Innovative and Transformational Seed (HITS) Fund initiative.

New experimental technique developed by Penn State researchers helps uncover how certain proteins cooperate to bind to otherwise closed regions of the genome to facilitate cell differentiation and development. Illustration shows expanded view of chromosome from a cell at the upper left. The “pioneer factor” FOXA1 co-binds with AP-1, allowing FOXA1 to locate target sites in the genome with high specificity. Credit: Holly Godin/Bai Laboratory / Penn State.

Genomic pioneers collaborate to access the inaccessible

A new experimental method allows researchers to dissect how certain proteins, called pioneer factors, can bind to selective regions of the genome that are inaccessible to other DNA binding proteins.

Research teams receive $1.1 million to study microbiomes in agriculture

Two Penn State-led research teams have received funding from the U.S. Department of Agriculture’s National Institute of Food and Agriculture for projects investigating the ways microbiomes — the microorganisms in a particular environment, such as in soil or a living organism — can affect disease dynamics in agriculture.

New CMIND director named

Janine Kwapis, the Paul Berg Early Career Professor in the Biological Sciences at Penn State, has been appointed director of the University's Center for Molecular Investigation of Neurological Disorders (CMIND), an interdisciplinary research unit within the Huck Institutes of the Life Sciences

Cancer drug could treat early-stage Alzheimer’s disease, study shows

A type of drug developed for treating cancer holds promise as a new treatment for neurodegenerative diseases such as Alzheimer’s, according to a recent study by researchers at Penn State, Stanford University and an international team of collaborators.

Honey bees may play role in spreading viruses to wild bumble bees

Honey bees may play a role in increasing virus levels in wild bumble bees each spring, according to researchers at Penn State who analyzed seasonal trends of parasite and virus transmission in bees.

Rewriting the evolutionary history of critical components of the nervous system

A new study has rewritten the conventionally understood evolutionary history of certain proteins critical for electrical signaling in the nervous system. The study, led by Penn State researchers, shows that the well-studied family of proteins — potassium ion channels in the Shaker family — were present in microscopic single cell organisms well before the common ancestor of all animals.

Memory problems in old age linked to a key enzyme, study in mice finds

A team of researchers from Penn State has identified an enzyme that contributes to age-related impairments in memory updating. When blocked, older mice were better able to incorporate new information and performed similarly to their younger counterparts. The researchers said the findings may lead to the development of potential therapeutic targets for improving cognitive flexibility in old age.

Biomedical engineer to use $2M NIH grant to improve human tissue repair

A team of Penn State researchers led by Wang was recently awarded a four-year, $2.02 million National Institutes of Health grant to explore how to safely add growth factors to collagen used by doctors for tissue repair.

Penn State researchers receive USDA-NIFA grant to study male cattle genetics

The U.S. Department of Agriculture (USDA) has awarded a grant to a team of researchers in the Penn State College of Agricultural Sciences to study the genetic mechanisms underlying the development of the testis, the male organ that produces reproductive cells, in cattle and its role in sperm production.