News

Nov 15, 2024

Q&A: How do microbiomes influence the study of life?

Microorganisms — bacteria, viruses and other tiny life forms — may drive biological variation in visible life as much, if not more, than genetic mutations, creating new lineages and even new species of animals and plants, according to Seth Bordenstein, director of Penn State’s One Health Microbiome Center within the Huck Institutes of the Life Sciences.

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Nov 14, 2024

Three Penn State researchers awarded scientific grants from Kaufman Foundation

The Charles E. Kaufman Foundation — a supporting organization of The Pittsburgh Foundation, which works to improve the quality of life in the Pittsburgh region — has selected three Penn State researchers to receive scientific research grants. The foundation awards grants to scientists at institutes of higher learning in Pennsylvania who are conducting innovative, fundamental scientific research in the fields of biology, chemistry and physics.

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Nov 12, 2024

Uncharted territory: A Q&A with Nanyin Zhang on mapping brain activity

To understand how different regions of the brain work together, researchers use a method called resting-state functional magnetic resonance imaging (rsfMRI). The method measures brain activity by observing changes in blood flow to different parts of the brain; however, rsfMRI does not explain how these blood flow changes to different brain regions relate to what is happening with the brain’s neurons — cells that send and receive messages in the form of electronic signals.

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The novel Cleavage High-throughput Assay (CHiTA) developed at Penn State provides a scarless method to characterize thousands of diverse small self-cleaving RNA enzymes, called twister ribozymes, in a single experiment. The image shows 2D models of some of the tested ribozymes that had imperfections in their helical and loop elements but were still active, demonstrating that twister ribozyme's ability to self-cleave is tolerant of these slight structural imperfections. Credit: Lauren McKinley and Philip Bevilacqua / Penn State. Creative Commons

Nov 06, 2024

Testing thousands of RNA enzymes helps find first ‘twister ribozyme’ in mammals

A new method, developed by Penn State researchers, can test the activity of thousands of predicted ribozymes in a single experiment.

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Oct 31, 2024

Huck researchers reflect on the 2024 Nobel Prize in Chemistry

This month, the Nobel Prize in Chemistry was awarded to three scientists credited with historic breakthroughs surrounding proteins and their structures. Three Huck researchers working on similar challenges chime in with their thoughts.

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Gustavo Nader, professor of kinesiology and physiology in the Penn State College of Health and Human Development, has been named the Dorothy Foehr Huck and J. Loyd Huck Chair in Molecular, Cellular and Integrative Physiology by Huck Institutes of the Life Sciences. Credit: Huck Institutes of the Life Sciences. All Rights Reserved.

Oct 18, 2024

Gustavo Nader named Huck Chair in Molecular, Cellular and Integrative Physiology

Gustavo Nader, professor of kinesiology and physiology in the Penn State College of Health and Human Development, has been named the Dorothy Foehr Huck and J. Loyd Huck Chair in Molecular, Cellular and Integrative Physiology by the Huck Institutes of the Life Sciences.

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The researchers collected 58 bulk tank milk samples and applied various AI algorithms to differentiate between baseline samples and those representing potential anomalies, such as milk from an outside farm or milk containing antibiotics. Credit: SeanShot/Getty Images. All Rights Reserved.

Oct 11, 2024

AI decodes microbes’ message in milk safety testing approach

By combining the genetic sequencing and analysis of the microbes in a milk sample with artificial intelligence (AI), researchers were able to detect anomalies in milk production, such as contamination or unauthorized additives.

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While the findings are preliminary, the work is a promising first step in finding new therapies against tuberculosis, according to the researchers. Credit: Mathias Katz/Unsplash. All Rights Reserved.

Oct 02, 2024

Plant compound used in traditional medicine may help fight tuberculosis

A compound found in African wormwood — a plant used medicinally for thousands of years to treat many types of illness — could be effective against tuberculosis.

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The researchers tested raw sewage samples collected twice a week from two treatment plants in central Pennsylvania for non-typhoidal Salmonella and characterized isolates using whole genome sequencing. They recovered 43 Salmonella isolates from wastewater samples. Credit: Provided by Ed Dudley. All Rights Reserved.

Sep 20, 2024

Wastewater monitoring can detect foodborne illness, researchers find

Results of a new study suggest sewage monitoring could provide early warning of foodborne disease outbreaks to public health authorities

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Jasna Kovac, associate professor in food science, has been selected to receive the 2025 Award for Early Career Environmental Research by the American Society for Microbiology. Credit: Penn State. Creative Commons

Sep 17, 2024

Food science researcher receives early career award

Jasna Kovac, associate professor and Lester Earl and Veronica Casida Career Development Professor of Food Safety in Penn State’s College of Agricultural Sciences, has been selected to receive the 2025 Award for Early Career Environmental Research by the American Society for Microbiology.

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